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Articles Published Processes
8/27/2018 7:22:43 AM | Browse: 983 | Download: 1176
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Received |
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2018-05-07 01:08 |
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Peer-Review Started |
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2018-05-07 03:25 |
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To Make the First Decision |
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2018-05-17 02:46 |
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Return for Revision |
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2018-05-21 06:57 |
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Revised |
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2018-06-05 15:06 |
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Second Decision |
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2018-06-26 11:31 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-06-27 04:05 |
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Articles in Press |
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2018-06-27 04:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-07-05 19:09 |
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Typeset the Manuscript |
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2018-08-27 01:39 |
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Publish the Manuscript Online |
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2018-08-27 07:22 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Prognostic significance of tumor immune microenvironment and immunotherapy: Novel insights and future perspectives in gastric cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Daniela Cornelia Lazăr, Mihaela Flavia Avram, Ioan Romoșan, Mărioara Cornianu, Sorina Tăban and Adrian Goldiș |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Daniela Cornelia Lazăr, MD, PhD, Senior Lecturer, Department of Internal Medicine I, the University of Medicine and Pharmacy “Victor Babes” Timisoara, Piata Eftimie Murgu No.2, Timisoara 300041, Timiş County, Romania. lazar.daniela@umft.ro |
| Key Words |
Immunotherapy; Prognostic significance; Tumor immune microenvironment; Immune checkpoint inhibitors; Gastric cance |
| Core Tip |
The use of modern immunotherapy, including adoptive cell therapy, vaccines, and especially immune therapy using checkpoint inhibitors, has led to encouraging results in clinical trials including gastric cancer patients. This review analyzes the relationship between immune microenvironment profile of the host and tumor development, identification of the immune prognostic markers and future perspectives of immunotherapeutic strategies. The treatment algorithm should be adapted to the specific molecular profile of the gastric cancer subtype in order to obtain maximum clinical benefits. |
| Publish Date |
2018-08-27 07:22 |
| Citation |
Lazăr DC, Avram MF, Romoşan I, Cornianu M, Tăban S, Goldiş A. Prognostic significance of tumor immune microenvironment and immunotherapy: novel insights and future perspectives in gastric cancer. World J Gastroenterol 2018; 24(32): 3583-3616 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i32/3583.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i32.3583 |
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