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7/19/2018 7:04:34 AM | Browse: 433 | Download: 456
Publication Name World Journal of Gastroenterology
Manuscript ID 39640
Country/Territory China
2018-05-02 09:55
Peer-Review Started
2018-05-04 02:43
To Make the First Decision
2018-06-06 02:15
Return for Revision
2018-06-11 07:46
2018-06-28 16:21
Second Decision
2018-06-29 11:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-06-30 02:15
Articles in Press
2018-06-30 02:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-07-18 02:48
Publish the Manuscript Online
2018-07-19 07:04
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Review
Article Title MicroRNAs in the prognosis and therapy of colorectal cancer: From bench to bedside
Manuscript Source Invited Manuscript
All Author List Kenneth KW To, Christy WS Tong, Mingxia Wu and William CS Cho
Author(s) ORCID Number
Kenneth KW To http://orcid.org/0000-0003-2755-0283
Christy WS Tong http://orcid.org/0000-0003-2010-1418
Mingxia Wu http://orcid.org/0000-0002-6070-5569
William CS Cho http://orcid.org/0000-0003-4174-4586
Funding Agency and Grant Number
Funding Agency Grant Number
The Chinese University of Hong Kong, Faculty of Medicine 4054371
Corresponding Author Kenneth KW To, BPharm, PhD, Associate Professor, School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Room 801N, Lo Kwee Seong Integrated Biomedical Sciences Building, Area 39, Shatin, New Territories, Hong Kong , China. kennethto@cuhk.edu.hk
Key Words MicroRNA; Colorectal cancer; Multidrug resistance; Prognosis; Therapeutic target; Apoptosis; Metastasis; Recurrence; Risk stratification
Core Tip MicroRNAs (miRNAs) are important mediators regulating the initiation, progression, metastasis and recurrence of colorectal cancer (CRC). Numerous studies have reported dysregulation of miRNAs in tumor specimens and body fluids, including serum, plasma and feces. Furthermore, the miRNAs were more recently found in circulating exosomes from CRC patients. Fortunately, this finding suggests potential diagnostic, prognostic and therapeutic applications of miRNAs at different stages of CRC. In this review, we aim to outline the current body of knowledge pertaining to the critical roles played by miRNAs in the molecular pathogenesis of CRC. Our focus is to delineate practical applications of miRNAs as prognostic biomarkers and therapeutic targets in the treatment of CRC.
Publish Date 2018-07-19 07:04
Citation To KK, Tong CW, Wu M, Cho WC. MicroRNAs in the prognosis and therapy of colorectal cancer: From bench to bedside. World J Gastroenterol 2018; 24(27): 2949-2973
Url http://www.wjgnet.com/1007-9327/full/v24/i27/2949.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i27.2949
Full Article (PDF) WJG-24-2949.pdf
Full Article (Word) WJG-24-2949.doc
Manuscript File 39640-Review.docx
Answering Reviewers 39640-Answering reviewers.pdf
Audio Core Tip 39640-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 39640-Conflict-of-interest statement.pdf
Copyright License Agreement 39640-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 39640-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 39640-Language certificate.pdf
Peer-review Report 39640-Peer-review(s).pdf
Scientific Misconduct Check 39640-Scientific misconduct check.pdf
Scientific Editor Work List 39640-Scientific editor work list.pdf