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Articles Published Processes
7/19/2018 7:04:34 AM | Browse: 1203 | Download: 1953
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Received |
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2018-05-02 09:55 |
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Peer-Review Started |
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2018-05-04 02:43 |
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To Make the First Decision |
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2018-06-06 02:15 |
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Return for Revision |
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2018-06-11 07:46 |
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Revised |
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2018-06-28 16:21 |
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Second Decision |
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2018-06-29 11:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-06-30 02:15 |
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Articles in Press |
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2018-06-30 02:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-07-18 02:48 |
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Publish the Manuscript Online |
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2018-07-19 07:04 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
MicroRNAs in the prognosis and therapy of colorectal cancer: From bench to bedside
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Kenneth KW To, Christy WS Tong, Mingxia Wu and William CS Cho |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Chinese University of Hong Kong, Faculty of Medicine |
4054371 |
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| Corresponding Author |
Kenneth KW To, BPharm, PhD, Associate Professor, School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Room 801N, Lo Kwee Seong Integrated Biomedical Sciences Building, Area 39, Shatin, New Territories, Hong Kong , China. kennethto@cuhk.edu.hk |
| Key Words |
MicroRNA; Colorectal cancer; Multidrug resistance; Prognosis; Therapeutic target; Apoptosis; Metastasis; Recurrence; Risk stratification |
| Core Tip |
MicroRNAs (miRNAs) are important mediators regulating the initiation, progression, metastasis and recurrence of colorectal cancer (CRC). Numerous studies have reported dysregulation of miRNAs in tumor specimens and body fluids, including serum, plasma and feces. Furthermore, the miRNAs were more recently found in circulating exosomes from CRC patients. Fortunately, this finding suggests potential diagnostic, prognostic and therapeutic applications of miRNAs at different stages of CRC. In this review, we aim to outline the current body of knowledge pertaining to the critical roles played by miRNAs in the molecular pathogenesis of CRC. Our focus is to delineate practical applications of miRNAs as prognostic biomarkers and therapeutic targets in the treatment of CRC. |
| Publish Date |
2018-07-19 07:04 |
| Citation |
To KK, Tong CW, Wu M, Cho WC. MicroRNAs in the prognosis and therapy of colorectal cancer: From bench to bedside. World J Gastroenterol 2018; 24(27): 2949-2973 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i27/2949.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i27.2949 |
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