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Articles Published Processes
8/16/2018 11:54:24 AM | Browse: 1014 | Download: 1700
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Received |
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2018-05-03 02:27 |
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Peer-Review Started |
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2018-05-04 03:04 |
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To Make the First Decision |
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2018-05-21 02:33 |
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Return for Revision |
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2018-05-22 00:35 |
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Revised |
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2018-05-31 10:40 |
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Second Decision |
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2018-06-07 12:11 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-06-08 14:55 |
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Articles in Press |
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2018-06-08 14:55 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-08-10 07:51 |
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Publish the Manuscript Online |
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2018-08-16 11:54 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Risk factors for gastroesophageal reflux disease and analysis of genetic contributors
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Alexandra Argyrou, Evangelia Legaki, Christos Koutserimpas, Maria Gazouli, Ioannis Papaconstantinou, George Gkiokas and George Karamanolis |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Maria Gazouli, PhD, Associate Professor, Department of Basic Medical Sciences, Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Michalakopoulou 176, Athens 11527, Greece. mgazouli@med.uoa.gr |
| Key Words |
Single nucleotide polymorphisms; Genetic risk loci; Risk factors; Gastroesophageal reflux disease; Gastroesophageal reflux disease development |
| Core Tip |
Gastroesophageal reflux disease (GERD) is a common gastrointestinal disorder, which develops when the reflux of stomach contents causes troublesome symptoms and/or complications. Several risk factors of GERD have been identified and evaluated over the years. Motor esophageal and gastric abnormalities, along with anatomical factors could contribute to GERD development. Genetic contributors seem to play a major role in GERD. Numerous single-nucleotide polymorphisms in various genetic loci have been mentioned as potential risk factors. Further investigation on the risk genes may elucidate their exact function and role and demonstrate new therapeutic approaches to this increasingly common disease. |
| Publish Date |
2018-08-16 11:54 |
| Citation |
Argyrou A, Legaki E, Koutserimpas C, Gazouli M, Papaconstantinou I, Gkiokas G, Karamanolis G. Risk factors for gastroesophageal reflux disease and analysis of genetic contributors. World J Clin Cases 2018; 6(8): 176-182 |
| URL |
http://www.wjgnet.com/2307-8960/full/v6/i8/176.htm |
| DOI |
http://dx.doi.org/10.12998/wjcc.v6.i8.176 |
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