Publication Name	World Journal of Gastroenterology
Manuscript ID	39674
Country	China

Received	2018-05-09 03:59
Peer-Review Started	2018-05-09 05:56
First Decision by Editorial Office Director	2018-06-13 02:25
Return for Revision	2018-06-15 07:20
Revised	2018-06-28 09:19
Publication Fee Transferred
Second Decision by Editor	2018-06-29 11:30
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2018-06-30 02:15
Articles in Press	2018-06-30 02:15
Edit the Manuscript by Language Editor	2018-07-08 17:37
Typeset the Manuscript	2018-08-08 03:10
Publish the Manuscript Online	2018-08-13 07:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Research & Experimental Medicine
Manuscript Type	Basic Study
Article Title	Herb-partitioned moxibustion alleviates colon injuries in ulcerative colitis rats
Manuscript Source	Unsolicited Manuscript
All Author List	Dan Zhang, Yan-Bo Ren, Kai Wei, Jue Hong, Yan-Ting Yang, Li-Jie Wu, Ji Zhang, Zheng Shi, Huan-Gan wu and Xiao-Peng Ma
ORCID	Author(s) ORCID Number Dan Zhang http://orcid.org/0000-0003-0747-8691 Yan-Bo Ren http://orcid.org/0000-0003-0738-5591 Kai Wei http://orcid.org/0000-0003-1102-1117 Jue Hong http://orcid.org/0000-0002-9857-818X Yan-Ting Yang http://orcid.org/0000-0003-1388-4047 Li-Jie Wu http://orcid.org/0000-0003-3349-0918 Ji Zhang http://orcid.org/0000-0002-6016-1063 Zheng Shi http://orcid.org/0000-0003-0726-954X Huan-Gan wu http://orcid.org/0000-0003-0563-1560 Xiao-Peng Ma http://orcid.org/0000-0002-0582-3562
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81674073, 81202754, 81273843 National Key Basic Research Program of China 2015CB554501, 2009CB522900
Corresponding Author	Xiao-Peng Ma, PhD, Professor, Laboratory of Acupuncture-moxibustion and Immunology, Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, No. 650 South Wanping Road, Xuhui District, Shanghai 200030, China. pengpengma@163.com
Key Words	Cytokine expression profile; Ulcerative colitis; Protein microarray; Rats; Herb-partitioned moxibustion
Core Tip	Herb-partitioned moxibustion (HPM) has been shown to be effective in treating ulcerative colitis (UC) in recent years as a non-drug external therapy. In this study, we observed its effect on the expression profile of cytokines in UC rat colon. By protein functional cluster analysis and KEGG pathway analysis, we can conclude that the effect of HPM in promoting the repair of colon injuries of UC rats is plausibly related to the regulation of multiple abnormally-expressed cytokines, and the regulation of the signal pathways interacting between the cytokines and their receptors may be its significant immunological mechanism.
Publish Date	2018-08-13 07:45
Citation	Zhang D, Ren YB, Wei K, Hong J, Yang YT, Wu LJ, Zhang J, Shi Z, Wu HG, Ma XP. Herb-partitioned moxibustion alleviates colon injuries in ulcerative colitis rats. World J Gastroenterol 2018; 24(30): 3384-3397
URL	http://www.wjgnet.com/1007-9327/full/v24/i30/3384.htm
DOI	http://dx.doi.org/10.3748/wjg.v24.i30.3384

Full Article (PDF)	WJG-24-3384.pdf