Publication Name	World Journal of Gastroenterology
Manuscript ID	39751
Country	United Kingdom

Received	2018-05-09 02:49
Peer-Review Started	2018-05-09 06:00
To Make the First Decision	2018-06-13 05:03
Return for Revision	2018-06-15 08:00
Revised	2018-09-03 21:56
Second Decision	2018-09-27 06:30
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-10-05 23:30
Articles in Press	2018-10-05 23:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-10-18 03:04
Publish the Manuscript Online	2018-10-18 10:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Carcinogenesis on the background of liver fibrosis: Implications for the management of hepatocellular cancer
Manuscript Source	Invited Manuscript
All Author List	Joanne Marie O'Rourke, Vandana Mridhu Sagar, Tahir Shah and Shishir Shetty
ORCID	Author(s) ORCID Number Joanne Marie O'Rourke http://orcid.org/0000-0001-7851-0703 Vandana Mridhu Sagar http://orcid.org/0000-0003-2662-755X Tahir Shah http://orcid.org/0000-0002-0420-0304 Shishir Shetty http://orcid.org/0000-0002-4729-2173
Funding Agency and Grant Number
Corresponding Author	Shishir Shetty, MBChB, MRCP, PhD, Senior Research Fellow, Centre for Liver Research, Institute of Biomedical Research, University of Birmingham, Birmingham B15 2TT, United Kingdom. s.shetty@bham.ac.uk
Key Words	Hepatocellular cancer; Carcinogenesis; Inflammation; Fibrosis; Immunotherapy
Core Tip	In this review, we discuss the development of hepatocellular carcinoma in the setting of liver inflammation and fibrosis, reviewing the microenviron­ment that leads to this tumorigenic climate and the implications this has for patient management.
Publish Date	2018-10-18 10:13
Citation	O’Rourke JM, Sagar VM, Shah T, Shetty S. Carcinogenesis on the background of liver fibrosis: Implications for the management of hepatocellular cancer. World J Gastroenterol 2018; 24(39): 4436-4447
URL	http://www.wjgnet.com/1007-9327/full/v24/i39/4436.htm
DOI	http://dx.doi.org/10.3748/wjg.v24.i39.4436

Full Article (PDF)	WJG-24-4436.pdf
Full Article (Word)	WJG-24-4436.doc
Manuscript File	39751-Review.doc
Answering Reviewers	39751-Answering reviewers.pdf
Audio Core Tip	39751-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	39751-Conflict-of-interest statement.pdf
Copyright License Agreement	39751-Copyright license agreement.pdf
Peer-review Report	39751-Peer-review(s).pdf
Scientific Misconduct Check	39751-Scientific editor work list.pdf
Scientific Misconduct Check	39751-Scientific misconduct check.pdf