| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Low expression of CDK5RAP3 and DDRGK1 indicates a poor prognosis in patients with gastric cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jian-Xian Lin, Xin-Sheng Xie, Xiong-Feng Weng, Chao-Hui Zheng, Jian-Wei Xie, Jia-Bin Wang, Lu Jun, Qiyue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Ping Li and Chang-Ming Huang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Science Foundation of the Fujian Province, China |
2018J01307 |
| Startup Fund for Scientific Research, Fujian Medical University |
2016QH024 |
| Young and Middle-aged Talent Training Project of the Fujian Provincial Health and Family Planning Commission |
2014-ZQNJC-13 |
| Scientific and Technological Innovation Joint Capital Projects of Fujian Province |
2016Y9031 |
| Minimally invasive medical center of Fujian Province |
2011708# |
|
| Corresponding Author |
Chang-Ming Huang, MD, Doctor, Doctor, Professor, Department of Gastric Surgery, Fujian Medical University Union Hospital, No.29 Xinquan Road, Fuzhou 350001, Fujian Province, China. hcmlr2002@163.com |
| Key Words |
Gastric cancer; CDK5RAP3; DDRGK1; Prognosis |
| Core Tip |
The expression of CDK5RAP3 and DDRGK1 was down-regulated in gastric cancer tissues. Low expression CDK5RAP3 or DDRGK1 is a poor prognostic factor for gastric cancer patients. The co-expression of CDK5RAP3 and DDRGK1 is an independent prognostic factor for the overall survival of patients with gastric cancer. Moreover, we also found that co-expression of CDK5RAP3 and DDRGK1 can provide a more accurate model for the long-term prognosis of gastric cancer. |
| Publish Date |
2018-09-14 05:53 |
| Citation |
Lin JX, Xie XS, Weng XF, Zheng CH, Xie JW, Wang JB, Lu J, Chen QY, Cao LL, Lin M, Tu RH, Li P, Huang CM. Low expression of CDK5RAP3 and DDRGK1 indicates a poor prognosis in patients with gastric cancer. World J Gastroenterol 2018; 24(34): 3898-3907 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i34/3898.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i34.3898 |
