Publication Name	World Journal of Gastroenterology
Manuscript ID	3993
Country	Denmark

Received	2013-06-06 20:26
Peer-Review Started	2013-06-07 11:31
To Make the First Decision	2013-06-24 10:29
Return for Revision	2013-07-01 13:23
Revised	2013-07-09 16:55
Second Decision	2013-08-29 07:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-08-29 09:56
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-03 19:45
Publish the Manuscript Online	2013-11-18 10:59

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Pathophysiology of chronic pancreatitis
Manuscript Source	Invited Manuscript
All Author List	Christina Brock, Lecia Møller Nielsen, Dina Lelic and Asbjørn Mohr Drewes
Funding Agency and Grant Number	Funding Agency Grant Number Danish Council for Strategic Research
Corresponding Author	Christina Brock, DVM, PhD, Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Mølleparkvej 4, DK-9000 Aalborg, Denmark. cb@mech-sense.com
Key Words	Chronic pancreatitis; Pathogenesis; Risk factors; Etiology
Core Tip	The reported prevalence of chronic pancreatitis (CP) is approximately 0.5%. Etiological risk-factors associated with CP are multiple and throughout the review the M-ANNHEIM classification is used comprising environmental factors (alcohol consumption, nicotine habits and nutrition), hereditary, well characterized mutations, ductal obstruction and autoimmune factors. CP is characterized by progressive fibrotic destruction of glandular tissue, inflammation or duct obstruction, leading to irreversible functional impairment of both exocrine and endocrine functions. In view of the multi-factorial disease and the complex clinical picture, it is not surprising that treatment of patients with CP is challenging and often unsuccessful.
Publish Date	2013-11-18 10:59
Citation	Brock C, Nielsen LM, Lelic D, Drewes AM. Pathophysiology of chronic pancreatitis. World J Gastroenterol 2013; 19(42): 7231-7240
URL	http://www.wjgnet.com/1007-9327/full/v19/i42/7231.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i42.7231

Full Article (PDF)	WJG-19-7231.pdf
Manuscript File	3993-Review.docx
Answering Reviewers	3993-Answering reviewers.pdf
Copyright License Agreement	3993-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	3993-Language certificate.pdf
Peer-review Report	3993-Peer review(s).pdf
Scientific Editor Work List	3993-Scientific editor work list.doc