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9/6/2018 1:33:44 AM | Browse: 1029 | Download: 911
Publication Name World Journal of Gastroenterology
Manuscript ID 39970
Country/Territory Taiwan
Received
2018-05-22 11:07
Peer-Review Started
2018-05-23 07:49
To Make the First Decision
2018-06-13 06:12
Return for Revision
2018-06-15 07:31
Revised
2018-06-27 10:32
Second Decision
2018-07-13 08:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-07-16 01:42
Articles in Press
2018-07-16 01:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-07-19 18:35
Typeset the Manuscript
2018-08-31 09:13
Publish the Manuscript Online
2018-09-06 01:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Metabolomic alterations and chromosomal instability status in gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Cheng-Kun Tsai, Ta-Sen Yeh, Ren-Chin Wu, Ying-Chieh Lai, Meng-Han Chiang, Kuan-Ying Lu, Cheng-Yu Hung, Hung-Yao Ho, Mei-Ling Cheng and Gigin Lin
ORCID
Author(s) ORCID Number
Cheng-Kun Tsai http://orcid.org/0000-0002-9214-2801
Ta-Sen Yeh http://orcid.org/0000-0002-1830-9466
Ren-Chin Wu http://orcid.org/0000-0003-1439-0874
Ying-Chieh Lai http://orcid.org/0000-0003-0148-9488
Meng-Han Chiang http://orcid.org/0000-0002-2697-4757
Kuan-Ying Lu http://orcid.org/0000-0002-4677-9000
Cheng-Yu Hung http://orcid.org/0000-0003-4158-5079
Hung-Yao Ho http://orcid.org/0000-0001-5990-6622
Mei-Ling Cheng http://orcid.org/0000-0003-2006-133X
Gigin Lin http://orcid.org/0000-0001-7246-1058
Funding Agency and Grant Number
Funding Agency Grant Number
the Chang Gung Foundation CMRPG3E1321-2
the Chang Gung Foundation IRB201601916B0, IRB103-7448B
the Ministry of Science and Technology Taiwan MOST 106-2314-B-182A-019-MY3
Corresponding Author Gigin Lin, MD, PhD, Associate Professor, Department of Medical Imaging and Intervention, Imaging Core Lab, Institute for Radiological Research,, Chang Gung Memorial Hospital at Linkou and Chang Gung University, No.5, Fuxing St., Guishan Dist., Taoyuan 333, Taiwan. giginlin@gmail.com
Key Words Gastric cancer; Metabolomics; Oncogene; Copy-number; Chromosomal instability; Liquid chro­matography-mass spectrometry
Core Tip We studied the correlation of the compre­hensive metabolomic profiles of gastric cancer with its chromosomal instability (CIN) status. In this disease landscape study with no pre-specified hypothesis, we combined a gene molecule classification method with a metabolomics method to discover metabolic information for accurate tumor classification. CIN status-based metabolomic profiling has demonstrated translational potential in biomarker discovery and novel therapeutics development.
Publish Date 2018-09-06 01:33
Citation Tsai CK, Yeh TS, Wu RC, Lai YC, Chiang MH, Lu KY, Hung CY, Ho HY, Cheng ML, Lin G. Metabolomic alterations and chromosomal instability status in gastric cancer. World J Gastroenterol 2018; 24(33): 3760-3769
URL http://www.wjgnet.com/1007-9327/full/v24/i33/3760.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i33.3760
Full Article (PDF) WJG-24-3760.pdf
Full Article (Word) WJG-24-3760.doc
Manuscript File 39970-Review.doc
Answering Reviewers 39970-Answering reviewers.pdf
Audio Core Tip 39970-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 39970-Conflict-of-interest statement.pdf
Copyright License Agreement 39970-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 39970-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 39970-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 39970-Language certificate.pdf
Supplementary Material 39970-Supplementary material.pdf
Peer-review Report 39970-Peer-review(s).pdf
Scientific Misconduct Check 39970-Scientific misconduct check.pdf
Scientific Editor Work List 39970-Scientific editor work list.pdf