| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Diagnostic value of elevated serum carbohydrate antigen 199 level in acute cholangitis secondary to choledocholithiasis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yong Mei, Li Chen, Ci-jun Peng, Jun Wang, Peng-Fei Zeng, Guo-Xing Wang, Wen-Ping Li, Yan-Qing Luo, Chao Du, Kai Liu, Kun Xiong, Kai Leng, Chun-Lin Feng and Ji-Hu Jia |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Guizhou Provincial Department of Health Science and Technology |
No. GZWJKJ2014-2-151 |
| the Science and Technology Fund of Guizhou Province |
No. QKH LH [2016] 7421 |
| Zunyi Science and Technology Research and Development Fund |
No. ZSKHS [2016] 06 |
|
| Corresponding Author |
Kai Leng, PhD, Chief Doctor, Professor, Department of Hepatopancreatobiliary Surgery, the Third Affiliated Hospital of Zunyi Medical University, 98 Fenghuang Load, Zunyi 563000, Guizhou Province, China. lengkai4757zsyy@163.com |
| Key Words |
Carbohydrate antigen 199; Tumor marker; Choledocholithiasis; Inflammatory marker; Diagnosis; Acute cholangitis |
| Core Tip |
Acute cholangitis is an acute inflammatory response to increased bile duct pressure and bacterial infection following biliary obstruction, whereas biliary obstruction is mostly caused by choledocholithiasis. Failure of timely predicting the onset of acute cholangitis may lose the chance for a minimally invasive surgery and result in a high mortality of the patients. In this study, a total of 727 choledocholithiasis patients were included, and the results suggest that abnormally elevated serum carbohydrate antigen 199 level has an important value in the diagnosis of acute cholangitis secondary to choledocholithiasis. It may be a specific inflammatory marker for acute cholangitis. As a convenient and rapid test, it is worthy to be applied in clinical settings. |
| Publish Date |
2018-09-28 10:31 |
| Citation |
Mei Y, Chen L, Peng CJ, Wang J, Zeng PF, Wang GX, Li WP, Luo YQ, Du C, Liu K, Xiong K, Leng K, Feng CL, Jia JH. Diagnostic value of elevated serum carbohydrate antigen 199 level in acute cholangitis secondary to choledocholithiasis. World J Clin Cases 2018; 6(11): 441-446 |
| URL |
http://www.wjgnet.com/2307-8960/full/v6/i11/441.htm |
| DOI |
http://dx.doi.org/10.12998/wjcc.v6.i11.441 |
