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Articles Published Processes
9/30/2018 7:38:56 AM | Browse: 1090 | Download: 1234
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Received |
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2018-05-30 07:09 |
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Peer-Review Started |
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2018-05-30 08:34 |
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To Make the First Decision |
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2018-07-12 00:56 |
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Return for Revision |
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2018-07-18 03:25 |
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Revised |
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2018-08-09 10:52 |
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Second Decision |
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2018-08-20 06:43 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-08-24 09:25 |
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Articles in Press |
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2018-08-24 09:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-09-05 18:00 |
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Typeset the Manuscript |
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2018-09-28 08:47 |
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Publish the Manuscript Online |
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2018-09-30 07:38 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Potential involvement of heat shock proteins in pancreatic-duodenal homeobox-1-mediated effects on the genesis of gastric cancer: A 2D gel-based proteomic study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Juan Ma, Bei-Bei Wang, Xiao-Yan Ma, Wei-Ping Deng, Li-Shu Xu and Wei-Hong Sha |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Guangdong Natural Science Fund; Guangdong General Hospital |
2016A030313765 |
| Guangdong medical scientific research fund |
A2017070 and A2017122 |
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| Corresponding Author |
Wei-Hong Sha, MD, PhD, Chief Doctor, Professor, Department of Gastroenterology and Hepatology, Guangdong General Hospital (Guangdong Academy of Medical Sciences), Guangdong Geriatrics Institute, 106 Zhongshan Er Road, Guangzhou 510080, Guangdong Province, China. shaweihong@gdghospital.com.cn |
| Key Words |
Pancreatic-duodenal homeobox-1; Heat shock proteins; Gastric cancer; Proteomics; Two-dimensional electrophoresis |
| Core Tip |
Using a pcDNA3.1(+)-pancreatic-duodenal homeobox-1 (PDX1) vector, a PDX1-overexpressed model was built. Seven differential proteins were identified in SGC-PDX1 by two-dimensional electrophoresis gel proteomics compared with those in SGC-pcDNA. Four heat shock proteins were identified and confirmed by immunoblotting. qRT-PCR analysis further revealed that the expression of the HSPs was post-translationally regulated by the PDX1 protein. This study suggests the potential involvement of HSPs in PDX1 mediated effects on gastric carcinogenesis. |
| Publish Date |
2018-09-30 07:38 |
| Citation |
Ma J, Wang BB, Ma XY, Deng WP, Xu LS, Sha WH. Potential involvement of heat shock proteins in pancreatic-duodenal homeobox-1-mediated effects on the genesis of gastric cancer: A 2D gel-based proteomic study. World J Gastroenterol 2018; 24(37): 4263-4271 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i37/4263.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i37.4263 |
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