Publication Name	World Journal of Gastroenterology
Manuscript ID	4019
Country	Netherlands

Received	2013-06-08 15:18
Peer-Review Started	2013-06-08 18:24
To Make the First Decision	2013-07-05 18:29
Return for Revision	2013-07-18 12:19
Revised	2013-09-02 14:54
Second Decision	2013-09-16 17:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-09-17 06:14
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-15 17:18
Publish the Manuscript Online	2013-11-13 08:37

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Surveillance for hepatocellular carcinoma in chronic liver disease: Evidence and controversies
Manuscript Source	Invited Manuscript
All Author List	Suzanne van Meer, Robert A de Man, Peter D Siersema and Karel J van Erpecum
Funding Agency and Grant Number
Corresponding Author	Karel J van Erpecum, MD, PhD, Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Po BOX 85500, 3508 GA Utrecht, The Netherlands. k.j.vanerpecum@umcutrecht.nl
Key Words	Hepatocellular carcinoma; Surveillance; Chronic liver disease
Core Tip	Hepatocellular carcinoma is a frequent phenomenon in cirrhotic patients. Survival is generally poor, and curative options only exist if the tumor is detected in an early stage (Barcelona Clinic Liver Cancer stage 0 or A). This review summarizes existing evidence for surveillance including ultrasound, other radiological modalities and various serum biomarkers, and current guideline recommendations for surveillance. Selection of the appropriate high risk populations remains an important tool for cost-effective surveillance.
Publish Date	2013-11-13 08:37
Citation	van Meer S, de Man RA, Siersema PD, van Erpecum KJ. Surveillance for hepatocellular carcinoma in chronic liver disease: Evidence and controversies. World J Gastroenterol 2013; 19(40): 6744-6756
URL	http://www.wjgnet.com/1007-9327/full/v19/i40/6744.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i40.6744

Full Article (PDF)	WJG-19-6744.pdf
Manuscript File	4019-Review.doc
Answering Reviewers	4019-Answering reviewers.pdf
Copyright License Agreement	4019-Copyright assignment.pdf
Peer-review Report	4019-Peer reviewer(s).pdf
Scientific Editor Work List	4019-Scientific editor work list.doc