Publication Name	World Journal of Clinical Cases
Manuscript ID	40191
Country	United States

Received	2018-06-06 01:27
Peer-Review Started	2018-06-06 03:05
To Make the First Decision	2018-08-01 03:27
Return for Revision	2018-08-03 01:54
Revised	2018-08-23 03:55
Second Decision	2018-08-30 08:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-08-30 18:57
Articles in Press	2018-08-30 18:57
Publication Fee Transferred
Edit the Manuscript by Language Editor	2018-09-08 20:32
Typeset the Manuscript	2018-10-23 07:35
Publish the Manuscript Online	2018-10-26 14:57

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Cancer and comorbidity: The role of leptin in breast cancer and associated pathologies
Manuscript Source	Invited Manuscript
All Author List	Amitabha Ray
ORCID	Author(s) ORCID Number Amitabha Ray http://orcid.org/0000-0003-1240-6887
Funding Agency and Grant Number
Corresponding Author	Amitabha Ray, MBBS, MD, PhD, Associate Professor, Lake Erie College of Osteopathic Medicine, Seton Hill University, 20 Seton Hill Drive, Greensburg, PA 15601, United States. aray@lecom.edu
Key Words	Hypertension; Obesity; Postmenopausal breast cancer; Comorbidity; Diabetes
Core Tip	Obesity and associated pathologies such as insulin resistance and metabolic syndrome are inter­related health disorders wherein a chronic low-grade inflammation persists. Perhaps this inflammatory con­dition is associated with the etiology and disease course of postmenopausal breast cancer, like other obe­sity-related diseases such as type-2 diabetes mellitus and hypertension. Often these diseases may coexist, and comorbidity worsens the prognosis of cancer patients. Leptin is an important adipokine (mainly released by fat cells), which may play a crucial role in these obesity-related diseases.
Publish Date	2018-10-26 14:57
Citation	Ray A. Cancer and comorbidity: The role of leptin in breast cancer and associated pathologies. World J Clin Cases 2018; 6(12): 483-492
URL	http://www.wjgnet.com/2307-8960/full/v6/i12/483.htm
DOI	http://dx.doi.org/10.12998/wjcc.v6.i12.483

Full Article (PDF)	WJCC-6-483.pdf
Full Article (Word)	WJCC-6-483.doc
Manuscript File	40191-Review.docx
Answering Reviewers	40191-Answering reviewers.pdf
Audio Core Tip	40191-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	40191-Conflict-of-interest statement.pdf
Copyright License Agreement	40191-Copyright license agreement.pdf
Supplementary Material	40191-Supplementary-Material-revision.docx
Peer-review Report	40191-Peer-review(s).pdf
Scientific Misconduct Check	40191-Scientific misconduct check.pdf
Scientific Editor Work List	40191-Scientific editor work list.pdf