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Articles Published Processes
9/27/2018 9:38:46 AM | Browse: 1027 | Download: 1486
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Received |
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2018-06-07 00:28 |
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Peer-Review Started |
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2018-06-07 09:17 |
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To Make the First Decision |
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2018-07-12 00:23 |
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Return for Revision |
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2018-07-12 07:15 |
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Revised |
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2018-07-19 11:32 |
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Second Decision |
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2018-08-02 10:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-08-04 20:31 |
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Articles in Press |
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2018-08-04 20:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-09-25 03:22 |
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Publish the Manuscript Online |
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2018-09-27 09:38 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Editorial |
Article Title |
Hepatitis C resistance to NS5A inhibitors: Is it going to be a problem?
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Manuscript Source |
Invited Manuscript |
All Author List |
Heidar Sharafi and Seyed Moayed Alavian |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Heidar Sharafi, BSc, MA, MPhil, MSc, PhD, Research Scientist, Baqiyatallah Research Center for Gastroenterology and Liver Diseases, Baqiyatallah University of Medical Sciences, Tehran 1415513651, Iran. h.sharafi@meldcenter.com |
Key Words |
Direct-acting antiviral agent; Hepatitis C; NS5A; Resistance; Treatment |
Core Tip |
Hepatitis C virus resistance to NS5A inhibitors is one of the main problems of treatment with NS5A inhibitors. While the treatment of NS5A inhibitor-naïve patients is feasible and efficient, retreatment of NS5A inhibitor-experienced patients is challenging. In the context of failure following treatment with NS5A inhibitor-containing regimens, NS5A resistance-associated substitution testing can help in clinical decision-making, while the usefulness of baseline NS5A resistance-associated substitution testing in NS5A inhibitor-naïve patients is in question. |
Publish Date |
2018-09-27 09:38 |
Citation |
Sharafi H, Alavian SM. Hepatitis C resistance to NS5A inhibitors: Is it going to be a problem? World J Hepatol 2018; 10(9): 543-548 |
URL |
http://www.wjgnet.com/1948-5182/full/v10/i9/543.htm |
DOI |
http://dx.doi.org/10.4254/wjh.v10.i9.543 |
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