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9/15/2014 11:27:00 AM | Browse: 1034 | Download: 913
Publication Name World Journal of Pharmacology
Manuscript ID 4025
Country United States
Received
2013-06-09 08:51
Peer-Review Started
2013-06-12 13:57
To Make the First Decision
2013-07-05 18:29
Return for Revision
2013-07-18 16:39
Revised
2013-08-17 03:24
Second Decision
2013-09-13 14:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-09-13 22:51
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-10-28 16:56
Publish the Manuscript Online
2013-12-18 16:32
ISSN 2220-3192 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pharmacology & Pharmacy
Manuscript Type Review
Article Title Roles of cholinergic receptors during attentional modulation of cue detection
Manuscript Source Invited Manuscript
All Author List Joshua A Burk
Funding Agency and Grant Number
Corresponding Author Joshua A Burk, Associate Professor, Department of Psychology, College of William and Mary, 540 Landrum Drive PO Box 8795, Williamsburg, VA 23187, United States. jabur2@wm.edu
Key Words 192 IgG-saporin; Acetylcholinesterase inhibitors; Alzheimer’s disease; Attention; Basal forebrain; Muscarinic; Nicotinic; Protein kinase C; Prefrontal cortex; Schizophrenia
Core Tip The corticopetal cholinergic system is critical for normal attentional processing. Disruption of this system is associated with cognitive deficits in several disorders. Thus, restoration of cortical cholinergic neurotransmission represents a reasonable target for treating some cognitive disorders. Evidence is presented that the muscarinic muscarinic-1 receptor and nicotinic receptor subtypes appear to be key targets for future investigations related to treating cognitive disorders. Future research into muscarinic-nicotinic receptor interactions, along with the role of second messenger systems, is needed to further develop appropriate strategies for restoring cortical cholinergic neurotransmission.
Publish Date 2013-12-18 16:32
Citation Burk JA. Roles of cholinergic receptors during attentional modulation of cue detection. World J Pharmacol 2013; 2(4): 84-91
URL http://www.wjgnet.com/2220-3192/full/v2/i4/84.htm
DOI http://dx.doi.org/10.5497/wjp.v2.i4.84
Full Article (PDF) WJP-2-84.pdf
Full Article (Word) WJP-2-84.doc
Manuscript File 4025-Review.docx
Answering Reviewers 4025-Answering reviewers.pdf
Copyright License Agreement 4025-Copyright assignment.pdf
Peer-review Report 4025-Peer reviewer(s).pdf
Scientific Editor Work List 4025-Scientific editor work list.doc