Publication Name	World Journal of Clinical Cases
Manuscript ID	40286
Country	South Korea

Received	2018-06-20 07:35
Peer-Review Started	2018-06-20 07:56
To Make the First Decision	2018-08-28 07:42
Return for Revision	2018-08-29 01:42
Revised	2018-09-15 04:59
Second Decision	2018-09-25 08:23
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-10-12 04:08
Articles in Press	2018-10-12 04:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-10-31 09:23
Publish the Manuscript Online	2018-11-06 10:20

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Role of bile acids in colon carcinogenesis
Manuscript Source	Invited Manuscript
All Author List	Thi Thinh Nguyen, Trong Thuan Ung, Nam Ho Kim and Young Do Jung
ORCID	Author(s) ORCID Number Thi Thinh Nguyen http://orcid.org/0000-0003-1870-7381 Trong Thuan Ung http://orcid.org/0000-0002-4446-4347 Nam Ho Kim http://orcid.org/0000-0002-3746-3952 Young Do Jung http://orcid.org/0000-0003-1209-6786
Funding Agency and Grant Number
Corresponding Author	Young Do Jung, MD, PhD, Professor, Department of Biochemistry, Chonnam National Universtiy Medical School, Seoyang Ro 264, Hwasun, Jeonnam 58138, South Korea. ydjung@chonnam.ac.kr
Key Words	Apoptosis resistance; Cancer stemness; Bile acids; Colorectal cancer; Reactive oxygen species; Angiogenesis
Core Tip	Even though there is a close relationship between a high concentration of bile acids (BAs) and high risk of colorectal cancer (CRC), the mechanism of BAs promoting colon carcinogenesis is still not fully understood. In this review paper, we discuss molecular mechanisms of BAs as CRC promoters, their role in CRC progression, the oncogenic genes and signaling pathways involved, and important therapies against BA-related CRC.
Publish Date	2018-11-06 10:20
Citation	Nguyen TT, Ung TT, Kim NH, Jung YD. Role of bile acids in colon carcinogenesis. World J Clin Cases 2018; 6(13): 577-588
URL	http://www.wjgnet.com/2307-8960/full/v6/i13/577.htm
DOI	http://dx.doi.org/10.12998/wjcc.v6.i13.577

Full Article (PDF)	WJCC-6-577.pdf
Full Article (Word)	WJCC-6-577.doc
Manuscript File	40286-Review.doc
Answering Reviewers	40286-Answering reviewers.pdf
Audio Core Tip	40286-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	40286-Conflict-of-interest statement.pdf
Copyright License Agreement	40286-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	40286-Language certificate.pdf
Peer-review Report	40286-Peer-review(s).pdf
Scientific Misconduct Check	40286-Scientific misconduct check.pdf
Scientific Editor Work List	40286-Scientific editor work list.pdf