Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	40374
Country	Japan

Received	2018-06-19 04:48
Peer-Review Started	2018-06-20 07:51
To Make the First Decision	2018-07-19 07:46
Return for Revision	2018-07-23 06:24
Revised	2018-08-01 04:14
Second Decision	2018-08-06 10:05
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-08-07 04:42
Articles in Press	2018-08-07 04:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-08-24 01:17
Publish the Manuscript Online	2018-08-30 06:53

ISSN	2219-2808 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Pediatrics
Manuscript Type	Minireviews
Article Title	Clinical features of acute kidney injury in patients with Kawasaki disease
Manuscript Source	Invited Manuscript
All Author List	Toru Watanabe
ORCID	Author(s) ORCID Number Toru Watanabe http://orcid.org/https://orcid.org/0000-0003-3326-4144
Funding Agency and Grant Number
Corresponding Author	Toru Watanabe, MD, PhD, Doctor, Doctor, Department of Pediatrics, Niigata City General Hospital, 463-7 Shumoku, Chuo-ku, Niigata City 950-1197, Japan. twata@hosp.niigata.niigata.jp
Key Words	Kawasaki disease; Acute kidney injury; Kidney involvement; Multiple organ dysfunction syndrome
Core Tip	Acute kidney injury (AKI) has rarely been reported in patients with Kawasaki disease (KD). We review the clinical characteristics of AKI in patients with KD and show that AKI is caused by a number of pathologic changes induced by KD. Patients with KD and AKI had good outcomes, despite the developed of multiple organ dysfunction syndrome. The possible mechanisms underlying the development of AKI in KD include T-cell-mediated immunologic abnormalities, renal and glomerular endothelial injury resulted from vasculitis, immune complex-mediated kidney injury, and capillary leak and the increased release of cytokines with myocardial dysfunction.
Publish Date	2018-08-30 06:53
Citation	Watanabe T. Clinical features of acute kidney injury in patients with Kawasaki disease. World J Clin Pediatr 2018; 7(3): 83-88
URL	http://www.wjgnet.com/2219-2808/full/v7/i3/83.htm
DOI	http://dx.doi.org/10.5409/wjcp.v7.i3.83

Full Article (PDF)	WJCP-7-83.pdf
Full Article (Word)	WJCP-7-83.doc
Manuscript File	40374-Review.docx
Answering Reviewers	40374-Answering reviewers.pdf
Audio Core Tip	40374-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	40374-Conflict-of-interest statement.pdf
Copyright License Agreement	40374-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	40374-Language certificate.pdf
Peer-review Report	40374-Peer-review(s).pdf
Scientific Misconduct Check	40374-Scientific misconduct check.pdf
Scientific Editor Work List	40374-Scientific editor work list.pdf