Publication Name	World Journal of Gastroenterology
Manuscript ID	40414
Country	Japan

Received	2018-06-21 08:44
Peer-Review Started	2018-06-21 09:19
To Make the First Decision	2018-07-25 01:26
Return for Revision	2018-07-31 06:25
Revised	2018-08-05 11:46
Second Decision	2018-08-20 06:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-08-24 09:18
Articles in Press	2018-08-24 09:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-09-17 01:09
Publish the Manuscript Online	2018-09-20 02:33

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Randomized Clinical Trial
Article Title	Usefulness of the clip-flap method of endoscopic submucosal dissection: A randomized controlled trial
Manuscript Source	Invited Manuscript
All Author List	Hiromitsu Ban, Mitsushige Sugimoto, Taketo Otsuka, Masaki Murata, Toshiro Nakata, Hiroshi Hasegawa, Osamu Inatomi, Shigeki Bamba and Akira Andoh
ORCID	Author(s) ORCID Number Hiromitsu Ban http://orcid.org/0000-0002-5782-9210 Mitsushige Sugimoto http://orcid.org/0000000291947392 Taketo Otsuka http://orcid.org/0000-0001-5023-9771 Masaki Murata http://orcid.org/0000-0002-4951-0584 Toshiro Nakata http://orcid.org/0000-0001-6644-3347 Hiroshi Hasegawa http://orcid.org/0000-0001-9590-5408 Osamu Inatomi http://orcid.org/0000-0002-5837-6575 Shigeki Bamba http://orcid.org/0000-0002-4108-5894 Akira Andoh http://orcid.org/0000000185332669
Funding Agency and Grant Number
Corresponding Author	Mitsushige Sugimoto, MD, PhD, Associate Professor, Division of Digestive Endoscopy, Shiga University of Medical Science Hospital, Seta Tsukinowa-cho, Otsu, Otsu 520-2192, Shiga, Japan. sugimo@belle.shiga-med.ac.jp
Key Words	Gastric cancer; Clip flap method; Endoscopic submucosal dissection; Procedure time; Complication; Randomized clinical trial
Core Tip	We conducted a prospective study to investigate efficacy of the clip-flap method of endoscopic submucosal dissection (ESD) for early-stage gastric tumor. Recently, although the efficacy of the clip-flap method for ESD of large colorectal tumors is shown, we failed to show advantage of clip-flap method in efficacy or safety compared with the conventional method. Efficacy of clip-flap method-assisted ESD for gastric tumors may be limited, especially in cases with large size of tumor and with difficulty to make mucosal flap.
Publish Date	2018-09-20 02:33
Citation	Ban H, Sugimoto M, Otsuka T, Murata M, Nakata T, Hasegawa H, Inatomi O, Bamba S, Andoh A. Usefulness of the clip-flap method of endoscopic submucosal dissection: A randomized controlled trial. World J Gastroenterol 2018; 24(35): 4077-4085
URL	http://www.wjgnet.com/1007-9327/full/v24/i35/4077.htm
DOI	http://dx.doi.org/10.3748/wjg.v24.i35.4077

Full Article (PDF)	WJG-24-4077.pdf
CONSORT 2010 Statement	40414-CONSORT 2010 statement.pdf
Manuscript File	40414-Review.docx
Answering Reviewers	40414-Answering reviewers.pdf
Audio Core Tip	40414-Audio core tip.mp3
Biostatistics Review Certificate	40414-Biostatistics statement.pdf
Clinical Trial Registration Statement	40414-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form	40414-Conflict-of-interest statement.pdf
Copyright License Agreement	40414-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	40414-Approved-Grant-Application-Form(s)-or-Funding-Agency-Copy-of-any-Approval-Document(s)-revision.pdf
Signed Informed Consent Form(s) or Document(s)	40414-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	40414-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	40414-Language certificate.pdf
Peer-review Report	40414-Peer-review(s).pdf
Scientific Misconduct Check	40414-Scientific misconduct check.pdf
Scientific Editor Work List	40414-Scientific editor work list.pdf