| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Risk of lymph node metastases in patients with T1b oesophageal adenocarcinoma: A retrospective single centre experience
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
David Graham, Nejc Sever, Cormac Magee, William Waddingham, Matthew Banks, Rami Sweis, Hannah Al-Yousuf, Miriam Mitchison, Durayd Alzoubaidi, M Rodriguez-Justo, Laurence Lovat, MR Novelli, Marnix Jansen and Rehan Haidry |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
David Graham, BSc, MBBS, MRCP, Doctor, Doctor, GI Services, University College London Hospital, 235 Euston Road, London NW1 2BU, United Kingdom. david.graham14@nhs.net |
| Key Words |
Oesophageal adenocarcinoma; Submucosal invasion; T1b; Lymph node metastasis; Risk prediction; Endoscopy |
| Core Tip |
Our retrospective cohort data supports previously published work demonstrating that endoscopic therapy is a safe and effective option for T1b oesophageal adenocarcinoma without markers of high-risk for lymph-node metastasis. Furthermore, our work suggests that endoscopic therapy is a viable alternative to surgery in selected patients with high-risk lesions (particularly those with poor performance status) and highlights the need for further work exploring whether endoscopic therapy could be a viable option for all submucosal lesions. |
| Publish Date |
2018-11-07 02:30 |
| Citation |
Graham D, Sever N, Magee C, Waddingham W, Banks M, Sweis R, Al-Yousuf H, Mitchison M, Alzoubaidi D, Rodriguez-Justo M, Lovat L, Novelli M, Jansen M, Haidry R. Risk of lymph node metastases in patients with T1b oesophageal adenocarcinoma: A retrospective single centre experience. World J Gastroenterol 2018; 24(41): 4698-4707 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i41/4698.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i41.4698 |
