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Articles Published Processes
11/27/2018 5:55:53 AM | Browse: 1056 | Download: 2034
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Received |
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2018-09-11 01:35 |
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Peer-Review Started |
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2018-09-11 01:49 |
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First Decision by Editorial Office Director |
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2018-10-04 21:17 |
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Return for Revision |
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2018-10-11 01:19 |
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Revised |
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2018-10-20 13:46 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2018-11-02 09:24 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2018-11-02 16:56 |
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Articles in Press |
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2018-11-02 16:56 |
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Edit the Manuscript by Language Editor |
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2018-11-12 23:46 |
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Typeset the Manuscript |
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2018-11-27 01:59 |
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Publish the Manuscript Online |
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2018-11-27 05:55 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Development of a novel rat model of heterogeneous hepatic injury by injection with colchicine via the splenic vein
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan-Yan Zhang, Chao-Xu Zhang, Yu Li, Xuan Jiang, Yong-Fang Wang, Yang Sun, Jun Wang, Wan-Ying Ji and Yi Liu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yi Liu, PhD, Professor, Department of Radiology, First Affiliated Hospital of China Medical University, Heping District, No. 155 Nanjing Street, Shenyang 110001, Liaoning Province, China. liuyicmu@sina.cn |
| Key Words |
Heterogeneous hepatic injury; Rat model; Colchicine; T2-weighted images; Diffusion weighted imaging |
| Core Tip |
In this study, injection with colchicine via the splenic vein is shown to successfully develop a rat model of heterogeneous hepatic injury. Obvious pathological changes occurred in the hepatic parenchyma in the colchicine group. A significant difference was observed in liver injury scores, apparent diffusion coefficient values, and liver-to-muscle ratios of T2-weighted images (T2WI) between the left and right lobes in the colchicine group (P < 0.05). Our study suggested that diffusion weighted imaging and T2WI can be used to evaluate the heterogeneous injury among liver lobes. |
| Publish Date |
2018-11-27 05:55 |
| Citation |
Zhang YY, Zhang CX, Li Y, Jiang X, Wang YF, Sun Y, Wang J, Ji WY, Liu Y. Development of a novel rat model of heterogeneous hepatic injury by injection with colchicine via the splenic vein. World J Gastroenterol 2018; 24(44): 5005-5012 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i44/5005.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i44.5005 |
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