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Articles Published Processes
10/18/2018 10:13:24 AM | Browse: 964 | Download: 2358
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Received |
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2018-06-29 07:14 |
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Peer-Review Started |
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2018-07-02 09:36 |
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To Make the First Decision |
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2018-07-18 01:00 |
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Return for Revision |
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2018-07-18 07:29 |
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Revised |
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2018-07-27 19:58 |
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Second Decision |
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2018-08-20 08:14 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-08-24 09:13 |
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Articles in Press |
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2018-08-24 09:13 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-10-08 09:24 |
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Typeset the Manuscript |
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2018-10-18 03:04 |
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Publish the Manuscript Online |
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2018-10-18 10:13 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Molecular evaluation of glutathione S transferase family genes in patients with sporadic colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Gabriela Helena Rodrigues-Fleming, Glaucia Maria Mendonça Fernandes, Anelise Russo, Patrícia Matos Biselli-Chicote, João Gomes Netinho, Érika Cristina Pavarino and Eny Maria Goloni-Bertollo |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| São Paulo Research Foundation (FAPESP) |
2011/23969-1 |
| São Paulo Research Foundation (FAPESP) |
2012/02473-0 |
| National Council of Technological and Scientific Development (CNPq) |
310582/2014-8 |
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| Corresponding Author |
Eny Maria Goloni-Bertollo, PhD, Postdoc, Molecular Biology, Sao Jose Rio Preto Medical School, Av. Brigadeiro Faria Lima, - 5416 - Vila São Pedro, São José do Rio Preto 15090-000, São Paulo, Brazil. eny.goloni@famerp.br |
| Key Words |
Colorectal neoplasms; Smoking; Alcohol; Glutathione S transferase; Genetic polymorphisms |
| Core Tip |
Sporadic colorectal cancer (SCRC) is the third most common cancer worldwide and includes malignancies that occur in the colon and rectum. Age greater than 60 years, smoking, and alcohol habits are some of the risk factors for SCRC. Detoxification and elimination of carcinogens contained in tobacco and alcohol require metabolic activation mediated by enzymes that metabolize the xenobiotics (XME). Polymorphisms in genes such as GSTP1, GSTT1, and GSTM1 that encode enzymes involved in XMEs may be related to important processes in colorectal carcinogenesis. |
| Publish Date |
2018-10-18 10:13 |
| Citation |
Rodrigues-Fleming GH, Fernandes GMM, Russo A, Biselli-Chicote PM, Netinho JG, Pavarino ÉC, Goloni-Bertollo EM. Molecular evaluation of glutathione S transferase family genes in patients with sporadic colorectal cancer. World J Gastroenterol 2018; 24(39): 4462-4471 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i39/4462.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i39.4462 |
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