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Articles Published Processes
11/6/2018 10:20:22 AM | Browse: 1019 | Download: 1866
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Received |
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2018-08-07 02:45 |
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Peer-Review Started |
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2018-08-07 10:17 |
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First Decision by Editorial Office Director |
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2018-08-24 05:47 |
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Return for Revision |
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2018-08-28 07:09 |
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Revised |
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2018-09-10 19:33 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2018-09-12 09:50 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2018-10-09 19:14 |
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Articles in Press |
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2018-10-09 19:14 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-10-31 10:05 |
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Publish the Manuscript Online |
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2018-11-06 10:20 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Case Report |
| Article Title |
Successful rescue of acute liver failure and hemophagocytic lymphohistiocytosis following varicella infection: A case report and review of literature
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li-Na Zhang, Wei Guo, Ji-Hong Zhu and Yang Guo |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Capital Characteristic Clinic Project |
Z161100000516045 |
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| Corresponding Author |
Yang Guo, MD, Professor, Department of Emergency, Peking University People's Hospital, 11 Xizhimen South St, Beijing 100044, China. edguoyang@163.com |
| Key Words |
Acute liver failure; Immune dysregulation; Hyperferritinemia; Hemophagocytic lymphohistiocytosis; Varicella infection; Skin rash |
| Core Tip |
Herein we report a case of acute liver failure (ALF) and hemophagocytic lymphohistiocytosis (HLH) induced by varicella infection, successfully rescued by a combination therapy of acyclovir and immunosuppression with dexamethasone and etoposide. Accumulating evidence pointed towards a similar immune dysregulation pattern in ALF and HLH. Given the rarity, high mortality, and complexity of HLH in the context of ALF, it is important to maintain a high suspicion for HLH in ALF with or without an identified trigger. Patients might benefit from therapies targeted to halt any underlying trigger and control the overactive immune system. |
| Publish Date |
2018-11-06 10:20 |
| Citation |
Zhang LN, Guo W, Zhu JH, Guo Y. Successful rescue of acute liver failure and hemophagocytic lymphohistiocytosis following varicella infection: A case report and review of literature. World J Clin Cases 2018; 6(13): 659-665 |
| URL |
http://www.wjgnet.com/2307-8960/full/v6/i13/659.htm |
| DOI |
http://dx.doi.org/10.12998/wjcc.v6.i13.659 |
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