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11/9/2018 12:43:15 AM | Browse: 826 | Download: 1270
Publication Name World Journal of Clinical Oncology
Manuscript ID 40681
Country Mexico
Received
2018-07-06 00:20
Peer-Review Started
2018-07-06 02:28
To Make the First Decision
2018-08-06 09:07
Return for Revision
2018-08-07 02:36
Revised
2018-10-18 00:14
Second Decision
2018-10-23 01:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-10-24 04:10
Articles in Press
2018-10-24 04:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-11-06 07:18
Publish the Manuscript Online
2018-11-09 00:43
ISSN 2218-4333 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Control Study
Article Title Mismatch repair protein expression and intratumoral budding in rectal cancer are associated with an increased pathological complete response to preoperative chemoradiotherapy: A case-control study
Manuscript Source Invited Manuscript
All Author List Leonardo S Lino-Silva, Armando Gamboa-Domínguez, Diego Zúñiga-Tamayo, Rosa A Salcedo-Hernández, Lucely Cetina and David Cantú-de-León
ORCID
Author(s) ORCID Number
Leonardo S Lino-Silva http://orcid.org/0000-0002-7394-5123
Armando Gamboa-Domínguez http://orcid.org/0000-0002-1983-0384
Diego Zúñiga-Tamayo http://orcid.org/0000-0001-5774-8421
Rosa A Salcedo-Hernández http://orcid.org/0000-0003-4537-8034
Lucely Cetina http://orcid.org/0000-0003-2018-7338
David Cantú-de-León http://orcid.org/0000-0003-4171-239X
Funding Agency and Grant Number
Corresponding Author Leonardo S Lino-Silva, MSc, Academic Research, Doctor, Gastrointestinal Pathology Division, Instituto Nacional de Cancerología de México (Mexico's National Cancer Institute), Av. San Fernando # 22, Sección XVI, Tlalpan, Mexico City 14080, Mexico. saul.lino.sil@gmail.com
Key Words Rectal cancer; Chemoradiotherapy; Tumor budding; Mismatch repair; Pathologic complete response
Core Tip Defective Mismatch repair (dMMR) and a low number of buds in the pretreatment biopsy were independently associated with a high rate of the pathological complete response. Tumor budding and MMR status should be considered as tools to be implemented in studies that predict the pathological response to preoperative chemo-radiotherapy in rectal cancer.
Publish Date 2018-11-09 00:43
Citation Lino-Silva LS, Gamboa-Domínguez A, Zúñiga-Tamayo D, Salcedo-Hernández RA, Cetina L, Cantú-de-León D. Mismatch repair protein expression and intratumoral budding in rectal cancer are associated with an increased pathological complete response to preoperative chemoradiotherapy: A case-control study. World J Clin Oncol 2018; 9(7): 133-139
URL http://www.wjgnet.com/2218-4333/full/v9/i7/133.htm
DOI http://dx.doi.org/10.5306/wjco.v9.i7.133
Full Article (PDF) WJCO-9-133.pdf
Full Article (Word) WJCO-9-133.doc
STROBE Statement 40681-STROBE Statement.pdf
Manuscript File 40681-Review.doc
Answering Reviewers 40681-Answering-Reviewers-revision_1305.doc
Audio Core Tip 40681-Audio-Core-Tip-revision_1234.docx
Biostatistics Review Certificate 40681-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 40681-Conflict-of-interest statement.pdf
Copyright License Agreement 40681-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 40681-Signed-Informed-Consent-Form(s)-or-Document(s)-revision.pdf
Institutional Review Board Approval Form or Document 40681-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 40681-Language certificate.pdf
Peer-review Report 40681-Peer-review(s).pdf
Scientific Misconduct Check 40681-Scientific misconduct check.pdf
Scientific Editor Work List 40681-Scientific editor work list.pdf