ISSN |
2307-8960 (online) |
Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Medicine, Research & Experimental |
Manuscript Type |
Meta-Analysis |
Article Title |
Photodynamic therapy for middle-advanced stage upper gastrointestinal carcinomas: A systematic review and meta-analysis
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Bo Chen, Li Xiong, Wei-Dong Chen, Xiao-Hua Zhao, Jun He, Yan-Wen Zheng, Fan-Hua Kong, Xi Liu, Zi-Jian Zhang and Xiong-Ying Miao |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
the National Natural Science Foundation of China |
No. 81372628, No. 81773293 and No.31660266 |
the Natural Science Foundation of Hunan Province |
No. 12JJ5048 |
the Science and Technology Plan Fund in Hunan Province, P.R. China |
No. 2018JJ3758, No. 2017WK2063, No. 2017DK2011 |
the Science and Technology Plan Fund in Hunan Province, P.R. China |
No. 2015GK3117 and No. 2014WK2016 |
|
Corresponding Author |
Xiong-Ying Miao, MD, Professor, Department of General Surgery, The Second Xiangya Hospital , Central South University, No.139 Middle Renmin Road, Changsha 410011, Hunan Province, China. miaoxiongying3016@csu.edu.cn |
Key Words |
Photodynamic therapy; Radiotherapy; Chemotherapy; Upper gastrointestinal tract; Nd:YAG laser; Gastrointestinal neoplasm; Gastrointestinal diseases; Meta-analysis |
Core Tip |
Photodynamic therapy (PDT) is minimally invasive compared with chemotherapy and radiotherapy for the treatment of cancers. Limited data exist regarding the efficacy of PDT alone or combined with radiotherapy and chemotherapy for the treatment of middle-advanced stage upper gastrointestinal carcinomas. Therefore, we performed a systematic review and meta-analysis of ten available randomized controlled clinical trials that addressed the efficacy of PDT alone or combined with radiotherapy and chemotherapy in patients with middle-advanced stage upper gastrointestinal carcinomas. Our analysis showed that PDT may be suitable for single or combined treatment of middle-advanced stage upper gastrointestinal carcinomas, especially for elderly patients, those with severe diseases, those with severe complications, and those unwilling to undergo surgery. |
Publish Date |
2018-11-06 10:20 |
Citation |
Chen B, Xiong L, Chen WD, Zhao XH, He J, Zheng YW, Kong FH, Liu X, Zhang ZJ, Miao XY. Photodynamic therapy for middle-advanced stage upper gastrointestinal carcinomas: A systematic review and meta-analysis. World J Clin Cases 2018; 6(13): 650-658 |
URL |
http://www.wjgnet.com/2307-8960/full/v6/i13/650.htm |
DOI |
http://dx.doi.org/10.12998/wjcc.v6.i13.650 |