Publication Name	World Journal of Methodology
Manuscript ID	40802
Country	Romania

Received	2018-07-09 01:14
Peer-Review Started	2018-07-09 09:18
To Make the First Decision	2018-08-03 00:26
Return for Revision	2018-08-03 03:14
Revised	2018-08-17 17:18
Second Decision	2018-09-06 11:01
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-10-09 12:50
Articles in Press	2018-10-09 12:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-11-25 09:03
Publish the Manuscript Online	2018-11-29 08:39

ISSN	2222-0682 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Anatomy & Morphology
Manuscript Type	Editorial
Article Title	Precision medicine allergy immunoassay methods for assessing immunoglobulin E sensitization to aeroallergen molecules
Manuscript Source	Invited Manuscript
All Author List	Florin-Dan Popescu and Mariana Vieru
ORCID	Author(s) ORCID Number Florin-Dan Popescu http://orcid.org/0000-0001-6316-3155 Mariana Vieru http://orcid.org/0000-0001-7396-5688
Funding Agency and Grant Number
Corresponding Author	Florin-Dan Popescu, MD, PhD, Associate Professor, Chief Doctor, Department of Allergology and Clinical Immunology, “Nicolae Malaxa” Clinical Hospital, Sos Vergului 12, Sector 2, Bucharest 022441, Romania. florindanpopescu@ymail.com
Key Words	Singleplex; Multiplex; Immunoglobulin E sensitization; Aeroallergens; Immunoassays
Core Tip	Allergic respiratory diseases affect many people of all ages worldwide, showing increased prevalence, severity and complexity. New generation immunoassays using allergenic molecules represent a great precision medicine approach in research and clinical practice, allowing in vitro assessment of the immunoglobulin E (IgE) sensitization pattern at the molecular level, with favorable impact on allergy diagnosis and treatment, especially in selected patients with multiple aeroallergen sensitizations. The choice for a specific IgE immunoassay (singleplex, multiparameter or multiplex) for the allergenic extracts and molecular specificities, and the correct interpretation of the results, require optimal knowledge of the tests’ methodologies and characteristics, and good clinical judgments.
Publish Date	2018-11-29 08:39
Citation	Popescu FD, Vieru M. Precision medicine allergy immunoassay methods for assessing immunoglobulin E sensitization to aeroallergen molecules. World J Methodol 2018; 8(3): 17-36
URL	http://www.wjgnet.com/2222-0682/full/ v8/i3/17.htm
DOI	http://dx.doi.org/10.5662/wjm.v8.i3.17

Full Article (PDF)	WJM-8-17.pdf
Full Article (Word)	WJM-8-17.doc
Manuscript File	40802-Review.docx
Answering Reviewers	40802-Answering reviewers.pdf
Audio Core Tip	40802-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	40802-Conflict-of-interest statement.pdf
Copyright License Agreement	40802-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	40802-Language certificate.pdf
Peer-review Report	40802-Peer-review(s).pdf
Scientific Misconduct Check	40802-Scientific misconduct check.pdf
Scientific Editor Work List	40802-Scientific editor work list.pdf