Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	40946
Country	Canada

Received	2018-07-16 02:17
Peer-Review Started	2018-07-17 06:37
To Make the First Decision	2018-08-09 00:39
Return for Revision	2018-08-13 01:38
Revised	2018-09-13 20:35
Second Decision	2018-09-19 07:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-10-12 02:37
Articles in Press	2018-10-12 02:37
Publication Fee Transferred
Edit the Manuscript by Language Editor	2018-10-17 02:01
Typeset the Manuscript	2019-01-14 08:37
Publish the Manuscript Online	2019-01-15 08:49

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Systematic Reviews
Article Title	Gut-associated lymphoid tissue or so-called “dome” carcinoma of the colon: Review
Manuscript Source	Unsolicited Manuscript
All Author List	Aoife J McCarthy and Runjan Chetty
ORCID	Author(s) ORCID Number Aoife J McCarthy http://orcid.org/0000-0003-0806-0924 Runjan Chetty http://orcid.org/0000-0002-2124-515X
Funding Agency and Grant Number
Corresponding Author	Aoife J McCarthy, Doctor, Doctor, Department of Anatomical Pathology, Laboratory Medicine Program, University Health Network, 200 Elizabeth Street, 11th Floor, Eaton Wing, Toronto ON M5G 2C4, Canada. aoife.mccarthy@uhn.ca
Key Words	Dome-type carcinoma; Gastrointestinal-associated lymphoid tissue carcinoma; Gut-associated lymphoid tissue; Lymphoglandular complex; Colorectal cancer
Core Tip	This review comprehensively presents the etiology, clinical features, macroscopic and pathological findings, and clinical significance of gut- or gastrointestinal-associated lymphoid tissue (GALT) or “dome” carcinoma of the colon. These lesions are thought to arise from the M-cells of the GALT (lymphoglandular complex) of the intestine. They have a characteristic endoscopic plaque- or “dome”-like appearance. Histologically, they are characterized by submucosal localization, a prominent lymphoid infiltrate with germinal center formation, and dilated glands lined by bland columnar epithelial cells with eosinophilic cytoplasm. There have been no reports of metastatic disease or local recurrence in patients with colonic GALT/dome-type carcinomas.
Publish Date	2019-01-15 08:49
Citation	McCarthy AJ, Chetty R. Gut-associated lymphoid tissue or so-called “dome” carcinoma of the colon: Review. World J Gastrointest Oncol 2019; 11(1): 59-70
URL	https://www.wjgnet.com/1948-5204/full/v11/i1/59.htm
DOI	https://dx.doi.org/10.4251/wjgo.v11.i1.59

Full Article (PDF)	WJGO-11-59.pdf
Full Article (Word)	WJGO-11-59.docx
PRISMA 2009 Checklist	40946-PRISMA 2009 Checklist.pdf
Manuscript File	40946-Review.docx
Answering Reviewers	40946-Answering reviewers.pdf
Audio Core Tip	40946-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	40946-Conflict-of-interest statement.pdf
Copyright License Agreement	40946-Copyright license agreement.pdf
Peer-review Report	40946-Peer-review(s).pdf
Scientific Misconduct Check	40946-Scientific misconduct check.pdf
Scientific Editor Work List	40946-Scientific editor work list.pdf