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Articles Published Processes
10/19/2018 9:33:35 AM | Browse: 856 | Download: 1155
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Received |
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2018-07-19 02:44 |
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Peer-Review Started |
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2018-07-19 12:49 |
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To Make the First Decision |
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2018-08-01 03:23 |
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Return for Revision |
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2018-08-07 02:09 |
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Revised |
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2018-08-09 15:08 |
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Second Decision |
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2018-08-27 10:02 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-08-28 02:16 |
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Articles in Press |
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2018-08-28 02:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-09-05 17:48 |
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Typeset the Manuscript |
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2018-10-10 01:52 |
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Publish the Manuscript Online |
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2018-10-19 09:33 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Review |
| Article Title |
Complement-mediated renal diseases after kidney transplantation - current diagnostic and therapeutic options in de novo and recurrent diseases
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Fedaey Abbas, Mohsen El Kossi, Jon Jin Kim, Ihab Sakr Shaheen, Ajay Sharma and Ahmed Halawa |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ahmed Halawa, FRSC, MD, Senior Lecturer, Sheffield Teaching Hospitals, Herries Road, Sheffield S5 7AU, United Kingdom. ahmed.halawa@sth.nhs.uk. |
| Key Words |
Complement-related diseases; Kidney transplantation; De novo; Recurrent diseases |
| Core Tip |
The recent progress in our understanding of the pathophysiology of complement-mediated diseases is gaining considerable popularity. Complement dysregulation due to inherited or acquired factors is currently the culprit mechanism. Several constitutional abnormalities usually trigger the process of recurrence, with a subsequent high rate of graft loss. The development of the terminal complement inhibitor “eculizumab” is a breakthrough in controlling abnormal complement activation. While diagnosing complement abnormalities is one challenge, treatment cost with this new agent is another major hurdle in any health care system. New lines of promising therapies are currently in the pipeline. |
| Publish Date |
2018-10-19 09:33 |
| Citation |
Abbas F, El Kossi M, Kim JJ, Shaheen IS, Sharma A, Halawa A. Complement-mediated renal diseases after kidney transplantation - current diagnostic and therapeutic options in de novo and recurrent diseases. World J Transplant 2018; 8(6): 203-219 |
| URL |
http://www.wjgnet.com/2220-3230/full/v8/i6/203.htm |
| DOI |
http://dx.doi.org/10.5500/wjt.v8.i6.203 |
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