Publication Name	World Journal of Critical Care Medicine
Manuscript ID	41060
Country	United States

Received	2018-08-06 01:21
Peer-Review Started	2018-08-07 00:58
To Make the First Decision	2018-10-08 06:52
Return for Revision	2018-10-10 01:54
Revised	2018-10-21 20:12
Second Decision	2018-11-07 11:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-11-07 20:04
Articles in Press	2018-11-07 20:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-11-26 06:20
Publish the Manuscript Online	2018-12-14 03:05

ISSN	2220-3141(online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Critical Care Medicine
Manuscript Type	Retrospective Study
Article Title	Intensive care unit complications and outcomes of adult patients with hemophagocytic lymphohistiocytosis: A retrospective study of 16 cases
Manuscript Source	Unsolicited Manuscript
All Author List	Sumit Kapoor, Christopher K Morgan, Muhammad Asim Siddique and Kalpalatha K Guntupalli
ORCID	Author(s) ORCID Number Sumit Kapoor http://orcid.org/0000-0002-5683-3445 Christopher K Morgan http://orcid.org/0000-0002-1505-9246 Muhammad Asim Siddique http://orcid.org/0000-0002-7098-467X Kalpalatha K Guntupalli http://orcid.org/0000-0003-0033-4097
Funding Agency and Grant Number
Corresponding Author	Sumit Kapoor, FCCP, MD, Assistant Professor, Department of Critical Care Medicine, Montefiore Medical Center, 111 EAST 210th ST, Bronx, NY 10467, United States. drkapoorsumit@gmail.com
Key Words	Lymphohistiocytosis; Cytopenia; Hypercytokinemia; Hemophagocytosis; Shock
Core Tip	Hemophagocytic Lymphohistiocytosis is a serious disorder in intensive care unit (ICU) with high morbidity and mortality. Septic shock, acute kidney injury and respiratory failure are the most common manifestations in ICU. We observed high incidence of bleeding complications and bloodstream infections. High index of suspicion is necessary for ICU patients with severe septic shock and multi organ failure who do not respond to standard treatment.
Publish Date	2018-12-14 03:05
Citation	Kapoor S, Morgan CK, Siddique MA, Guntupalli KK. Intensive care unit complications and outcomes of adult patients with hemophagocytic lymphohistiocytosis: A retrospective study of 16 cases. World J Crit Care Med 2018; 7(6): 73-83
URL	http://www.wjgnet.com/2220-3141/full/v7/i6/73.htm
DOI	http://dx.doi.org/10.5492/wjccm.v7.i6.73

Full Article (PDF)	WJCCM-7-73.pdf
Full Article (Word)	WJCCM-7-73.doc
Manuscript File	41060-Review.docx
Answering Reviewers	41060-Answering reviewers.pdf
Audio Core Tip	41060-Audio core tip.m4a
Biostatistics Review Certificate	41060-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	41060-Conflict-of-interest statement.pdf
Copyright License Agreement	41060-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	41060-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	41060-Institutional review board statement.pdf
Peer-review Report	41060-Peer-review(s).pdf
Scientific Misconduct Check	41060-Scientific misconduct check.pdf
Scientific Editor Work List	41060-Scientific editor work list.pdf