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10/26/2018 11:38:21 AM | Browse: 203 | Download: 173
Publication Name World Journal of Gastroenterology
Manuscript ID 41328
Country of Manuscript Source China
Received
2018-08-11 05:30
Peer-Review Started
2018-08-13 02:26
To Make the First Decision
2018-08-27 01:48
Return for Revision
2018-08-27 08:47
Revised
2018-09-02 15:40
Second Decision
2018-09-13 09:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-10-05 22:57
Articles in Press
2018-10-05 22:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-10-15 01:07
Typeset the Manuscript
2018-10-22 07:27
Publish the Manuscript Online
2018-10-26 11:38
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Helicobacter pylori promotes invasion and metastasis of gastric cancer by enhancing heparanase expression
Manuscript Source Unsolicited Manuscript
All Author List Li-Ping Liu, Xi-Ping Sheng, Tian-Kui Shuai, Yong-Xun Zhao, Bin Li and Yu-Min Li
ORCID
Author(s) ORCID Number
Li-Ping Liu http://orcid.org/0000-0002-8339-0256
Xi-Ping Sheng http://orcid.org/0000-0001-9641-7633
Tian-Kui Shuai http://orcid.org/0000-0001-6733-3377
Yong-Xun Zhao http://orcid.org/0000-0001-9448-1623
Bin Li http://orcid.org/0000-0002-7366-4997
Yu-Min Li http://orcid.org/0000-0002-9267-1412
Funding Agency and Grant Number
Funding Agency Grant Number
Natural Science Foundation of Gansu Province 1506RJZA255
Natural Science Foundation of China 81572437
Open Topics of the Key Laboratory of Biological Treatment and Regenerative Medicine in Gansu Province zdsyskfkt-201702
Corresponding author Yu-Min Li, MD, PhD, Chief Doctor, Professor, Key Laboratory of Digestive System Tumors of Gansu Province, The Second Clinical Medical School of Lanzhou University, No.82 Cuiyingmen, Chengguan District, Lanzhou 730000, Gansu Province, China. liym@lzu.edu.cn
Keywords Gastric cancer; Helicobacter pylori; He­paranase; Mitogen-activated protein kinase; Overall survival; Relapse-free survival
Core Tip The mechanism of Helicobacter pylori (H. pylori) infection in the invasion and metastasis of gastric cancer (GC) is still unknown. This paper studied heparanase (HPA) and mitogen-activated protein kinase (MAPK) expression in GC tissues and GC cells and their relationship with H. pylori infection. H. pylori infection may promote the invasion and metastasis of GC by increasing the expression of HPA that may be increased by activation of MAPK signal and HPA expression in GC tissue. H. pylori positive GC had a poorer prognosis.
Publish Date 2018-10-26 11:38
Citation Liu LP, Sheng XP, Shuai TK, Zhao YX, Li B, Li YM. Helicobacter pylori promotes invasion and metastasis of gastric cancer by enhancing heparanase expression. World J Gastroenterol 2018; 24(40): 4565-4577
Url http://www.wjgnet.com/1007-9327/full/v24/i40/4565.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i40.4565
Full Article (PDF) WJG-24-4565.pdf
Full Article (Word) WJG-24-4565.doc
Manuscript File 41328-Review.docx
Answering Reviewers 41328-Answering reviewers.pdf
Audio Core Tip 41328-Audio core tip.mp3
Biostatistics Review Certificate 41328-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 41328-Conflict-of-interest statement.pdf
Copyright License Agreement 41328-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 41328-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 41328-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 41328-Language certificate.pdf
Peer-review Report 41328-Peer-review(s).pdf
Scientific Misconduct Check 41328-Scientific misconduct check.pdf
Scientific Editor Work List 41328-Scientific editor work list.pdf