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Articles Published Processes
10/26/2018 11:38:21 AM | Browse: 878 | Download: 1236
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Received |
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2018-08-11 05:30 |
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Peer-Review Started |
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2018-08-13 02:26 |
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To Make the First Decision |
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2018-08-27 01:48 |
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Return for Revision |
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2018-08-27 08:47 |
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Revised |
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2018-09-02 15:40 |
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Second Decision |
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2018-09-13 09:05 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-10-05 22:57 |
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Articles in Press |
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2018-10-05 22:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-10-15 01:07 |
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Typeset the Manuscript |
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2018-10-22 07:27 |
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Publish the Manuscript Online |
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2018-10-26 11:38 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Basic Study |
Article Title |
Helicobacter pylori promotes invasion and metastasis of gastric cancer by enhancing heparanase expression
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Li-Ping Liu, Xi-Ping Sheng, Tian-Kui Shuai, Yong-Xun Zhao, Bin Li and Yu-Min Li |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Natural Science Foundation of Gansu Province |
1506RJZA255 |
Natural Science Foundation of China |
81572437 |
Open Topics of the Key Laboratory of Biological Treatment and Regenerative Medicine in Gansu Province |
zdsyskfkt-201702 |
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Corresponding Author |
Yu-Min Li, MD, PhD, Chief Doctor, Professor, Key Laboratory of Digestive System Tumors of Gansu Province, The Second Clinical Medical School of Lanzhou University, No.82 Cuiyingmen, Chengguan District, Lanzhou 730000, Gansu Province, China. liym@lzu.edu.cn |
Key Words |
Gastric cancer; Helicobacter pylori; Heparanase; Mitogen-activated protein kinase; Overall survival; Relapse-free survival |
Core Tip |
The mechanism of Helicobacter pylori (H. pylori) infection in the invasion and metastasis of gastric cancer (GC) is still unknown. This paper studied heparanase (HPA) and mitogen-activated protein kinase (MAPK) expression in GC tissues and GC cells and their relationship with H. pylori infection. H. pylori infection may promote the invasion and metastasis of GC by increasing the expression of HPA that may be increased by activation of MAPK signal and HPA expression in GC tissue. H. pylori positive GC had a poorer prognosis. |
Publish Date |
2018-10-26 11:38 |
Citation |
Liu LP, Sheng XP, Shuai TK, Zhao YX, Li B, Li YM. Helicobacter pylori promotes invasion and metastasis of gastric cancer by enhancing heparanase expression. World J Gastroenterol 2018; 24(40): 4565-4577 |
URL |
http://www.wjgnet.com/1007-9327/full/v24/i40/4565.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v24.i40.4565 |
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