Publication Name	World Journal of Gastroenterology
Manuscript ID	4154
Country	Egypt

Received	2013-06-17 11:05
Peer-Review Started	2013-06-18 15:14
To Make the First Decision	2013-08-08 11:28
Return for Revision	2013-08-16 19:41
Revised	2013-08-23 16:50
Second Decision	2013-09-03 14:31
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-09-04 07:43
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-10-16 17:15
Typeset the Manuscript	2013-10-29 18:22
Publish the Manuscript Online	2013-11-16 18:29

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Autobiography
Article Title	Impact of cirrhosis on surgical outcome after pancreaticoduodenectomy
Manuscript Source	Invited Manuscript
All Author List	Ayman El Nakeeb, Ahmad M Sultan, Tarek Salah, Mohamed El Hemaly, Emad Hamdy, Ali Salem, Ahmed Moneer, Rami Said, Ahmed AbuEleneen, Mostafa Abu Zeid, Talaat Abdallah and Mohamed Abdel Wahab
Funding Agency and Grant Number
Corresponding Author	Ayman El Nakeeb, MD, Associate Professor of general surgery, Gastroenterology surgical center, Mansoura University, Gehan street, Mansoura 35516, Egypt. elnakeebayman@yahoo.com
Key Words	Periampullary tumour; Liver cirrhosis; Portal hypertension; Pancreaticoduodenectomy
Core Tip	Traditionally, cirrhosis has been considered a contraindication to major gastrointestinal surgery. Hospital mortality rates have been reported to be 17.5 % to 38% for cirrhotic patients undergoing gastrointestinal surgery. Pancreaticoduodenectomy is associated with an increased risk of postoperative morbidity in patients with liver cirrhosis; therefore, it is recommended only in patients with Child A cirrhosis. Cirrhotic patients with portal hypertension were associated with poorer outcome than cirrhotic patients without portal hypertension. Patients with periampullary tumours and well-compensated chronic liver disease should be routinely considered for radical surgery at high volume centres with available expertise to manage liver cirrhosis.
Publish Date	2013-11-16 18:29
Citation	El Nakeeb A, Sultan AM, Salah T, El Hemaly M, Hamdy E, Salem A, Moneer A, Said R, AbuEleneen A, Abu Zeid M, Abdallah T, Abdel Wahab M. Impact of cirrhosis on surgical outcome after pancreaticoduodenectomy. World J Gastroenterol 2013; 19(41): 7129-7137
URL	http://www.wjgnet.com/1007-9327/full/v19/i41/7129.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i41.7129

Full Article (PDF)	WJG-19-7129.pdf
Manuscript File	4154-Review.docx
Answering Reviewers	4154-Answering reviewers.pdf
Copyright License Agreement	4154-Copyright assignment.pdf
Peer-review Report	4154-Peer review(s).pdf
Scientific Editor Work List	4154-Scientific editor work list.doc