Publication Name	World Journal of Cardiology
Manuscript ID	4156
Country	United States

Received	2013-06-17 11:23
Peer-Review Started	2013-06-18 15:23
To Make the First Decision	2013-07-05 18:19
Return for Revision	2013-07-15 22:58
Revised	2013-08-06 07:20
Second Decision	2013-10-11 14:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-10-12 00:30
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-10-23 18:35
Publish the Manuscript Online	2013-10-24 17:56

ISSN	1949-8462 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Letter to the Editor
Article Title	Circle of Willis atherosclerosis, Alzheimer’s disease and the Dean number
Manuscript Source	Invited Manuscript
All Author List	Rovshan M Ismailov
Funding Agency and Grant Number
Corresponding Author	Rovshan M Ismailov, MD, MPH, PhD, Research Scientist, Complex Mechanisms of Disease, Aging and Trauma Research Foundation, PO Box 461286, Glendale, CO 80246, United States. rovshani@yahoo.com
Key Words	Circle of Willis; Alzheimer’s disease; Atherosclerosis; Mechanism; The Dean number
Core Tip	The Dean number can become an important local pathophysiological mechanism that can help to explain the specific involvement of the Circle of Willis in atherosclerosis and Alzheimer’s Disease as anatomically different parts of the Circle of Willis would exhibit various degree of the curvature which would predispose to Alzheimer’s disease. This could possibly explain some sporadic cases of Alzheimer’s disease in the presence of minimal damage from atherosclerosis as well as open up new avenues for prevention of sporadic Alzheimer’s disease.
Publish Date	2013-10-24 17:56
Citation	Ismailov RM. Circle of Willis atherosclerosis, Alzheimer’s disease and the Dean number. World J Cardiol 2013; 5(10): 394-396
URL	http://www.wjgnet.com/1949-8462/full/v5/i10/394.htm
DOI	http://dx.doi.org/10.4330/wjc.v5.i10.394

Full Article (PDF)	WJC-5-394.pdf
Manuscript File	4156-Review.doc
Answering Reviewers	4156-Answering reviewers.pdf
Copyright License Agreement	4156-Copyright assignment.doc
Peer-review Report	4156-Peer review(s).pdf
Scientific Editor Work List	4156-Scientific editor work list.doc