Publication Name	World Journal of Biological Chemistry
Manuscript ID	41581
Country	Spain

Received	2018-08-15 01:52
Peer-Review Started	2018-08-17 09:14
To Make the First Decision	2018-09-11 08:09
Return for Revision	2018-09-11 08:43
Revised	2018-10-08 07:36
Second Decision	2018-10-23 02:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-10-23 23:58
Articles in Press	2018-10-23 23:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-11-08 01:17
Publish the Manuscript Online	2018-11-21 07:46

ISSN	1949-8454 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Biochemistry & Molecular Biology
Manuscript Type	Minireviews
Article Title	Role of STIM1 in neurodegeneration
Manuscript Source	Invited Manuscript
All Author List	Carlos Pascual-Caro, Noelia Espinosa-Bermejo, Eulalia Pozo-Guisado and Francisco Javier Martin-Romero
ORCID	Author(s) ORCID Number Carlos Pascual-Caro http://orcid.org/0000-0002-2345-393X Noelia Espinosa-Bermejo http://orcid.org/0000-0002-6976-0871 Eulalia Pozo-Guisado http://orcid.org/0000-0003-3486-6411 Francisco Javier Martin-Romero http://orcid.org/0000-0001-6796-7396
Funding Agency and Grant Number	Funding Agency Grant Number Spanish Ministerio de Ciencia, Innovación y Universidades BFU2017-82716-P
Corresponding Author	Francisco Javier Martin-Romero, PhD, Associate Professor, Department of Biochemistry and Molecular Biology, School of Life Sciences and Institute of Molecular Pathology Biomarkers, University of Extremadura, Avenida de Elvas s/n, Badajoz 06006, Spain. fjmartin@unex.es
Key Words	Alzheimer’s disease; Calcium; Neurodegeneration; Parkinson’s disease; STIM1; Voltage-operated Ca2+ channels
Core Tip	STIM1 is an endoplasmic reticulum protein that regulates store-operated Ca2+ entry, which is a Ca2+ influx pathway involved in a wide variety of signalling pathways. Growing evidence supports a role for this protein, STIM1, in long-term potentiation and the formation of memory. In this regard, the loss of STIM1 observed in brain tissue from Alzheimer’s disease patients risks cell viability and could be the cause of neurodegenerative diseases. This is the reason for discussing the role of STIM1 in neurodegeneration in this review.
Publish Date	2018-11-21 07:46
Citation	Pascual-Caro C, Espinosa-Bermejo N, Pozo-Guisado E, Martin-Romero FJ. Role of STIM1 in neurodegeneration. World J Biol Chem 2018; In press
URL	URL: http://www.wjgnet.com/1949-8454/full/v9/i2/16.htm
DOI	http://dx.doi.org/10.4331/wjbc.v9.i2.16

Full Article (PDF)	WJBC-9-16.pdf
Manuscript File	41581-Review.doc
Answering Reviewers	41581-Answering reviewers.pdf
Audio Core Tip	41581-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	41581-Conflict-of-interest statement.pdf
Copyright License Agreement	41581-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	41581-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	41581-Language certificate.pdf
Peer-review Report	41581-Peer-review(s).pdf
Scientific Misconduct Check	41581-Scientific misconduct check.pdf
Scientific Editor Work List	41581-Scientific editor work list.pdf