| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Incidence and treatment of mediastinal leakage after esophagectomy: Insights from the multicenter study on mediastinal leaks
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Uberto Fumagalli, Gian Luca Baiocchi, Andrea Celotti, Paolo Parise, Andrea Cossu, Luigi Bonavina, Daniele Bernardi, Giovanni de Manzoni, Jacopo Weindelmayer, Giuseppe Verlato, Stefano Santi, Giovanni Pallabazzer, Nazario Portolani, Maurizio Degiuli, Rossella Reddavid and Stefano de Pascale |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Uberto Fumagalli, MD, Director, Director, Surgical Oncologist, Department of Digestive Surgery, IEO European Institute of Oncology, Via Ripamonti 435, Milano 20141, Italy. ubertofumagalliromario@gmail.com |
| Key Words |
Transthoracic esophagectomy; Minimally invasive esophagectomy; Mediastinal leak; Esophagectomy complications |
| Core Tip |
Anastomotic mediastinal leaks represent one of the most feared complications of esophageal resection. The incidence of mediastinal leaks and their associated mortality rates are reported with great variability, and a standard strategy for the diagnosis and treatment has been difficult to establish. Data on all esophagectomies performed in seven Italian centers from 2014 to 2017 were collected and analyzed. The two take-home messages of our multicenter retrospective study are as follows: (1) the surgical approach significantly influenced the rate of mediastinal leaks, with the highest leakage rate occurring after totally minimally invasive esophagectomy and lowest rate occurring after hybrid esophagectomy; and (2) early (surgical or endoscopic) treatment of mediastinal leaks is an essential tool to address this complication and prevent other major complications of esophagectomy. |
| Publish Date |
2019-01-21 05:38 |
| Citation |
Fumagalli U, Baiocchi GL, Celotti A, Parise P, Cossu A, Bonavina L, Bernardi D, de Manzoni G, Weindelmayer J, Verlato G, Santi S, Pallabazzer G, Portolani N, Degiuli M, Reddavid R, de Pascale S. Incidence and treatment of mediastinal leakage after esophagectomy: Insights from the multicenter study on mediastinal leaks. World J Gastroenterol 2019; 25(3): 356-366 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i3/356.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i3.356 |
