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12/27/2018 8:56:32 AM | Browse: 113 | Download: 172
Publication Name World Journal of Gastroenterology
Manuscript ID 41644
Country of Manuscript Source Croatia
Received
2018-08-20 01:38
Peer-Review Started
2018-08-20 02:46
To Make the First Decision
2018-10-08 02:34
Return for Revision
2018-10-11 01:38
Revised
2018-12-05 19:18
Second Decision
2018-12-19 09:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-20 01:53
Articles in Press
2018-12-20 01:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-12-26 02:52
Publish the Manuscript Online
2018-12-27 08:56
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Counteraction of perforated cecum lesions in rats: Effects of pentadecapeptide BPC 157, L-NAME and L-arginine
Manuscript Source Invited Manuscript
All Author List Domagoj Drmic, Mariam Samara, Tinka Vidovic, Dominik Malekinusic, Marko Antunovic, Borna Vrdoljak, Jelena Ruzman, Marija Milkovic Perisa, Katarina Horvat Pavlov, Jerusha Jeyakumar, Sven Seiwerth and Predrag Sikiric
ORCID
Author(s) ORCID Number
Domagoj Drmic http://orcid.org/0000-0002-1081-7175
Mariam Samara http://orcid.org/0000-0003-2384-273X
Tinka Vidovic http://orcid.org/0000-0003-0092-9365
Dominik Malekinusic http://orcid.org/0000-0001-6258-5647
Marko Antunovic http://orcid.org/0000-0002-3801-5481
Borna Vrdoljak http://orcid.org/0000-0003-2306-8799
Jelena Ruzman http://orcid.org/0000-0002-9807-7270
Marija Milkovic Perisa http://orcid.org/0000-0002-9530-9208
Katarina Horvat Pavlov http://orcid.org/0000-0002-2661-7346
Jerusha Jeyakumar http://orcid.org/0000-0003-4883-3899
Sven Seiwerth http://orcid.org/0000-0002-5894-419X
Predrag Sikiric http://orcid.org/0000-0002-7952-2252
Funding Agency and Grant Number
Corresponding author Predrag Sikiric, MD, PhD, Professor, Department of Pharmacology, School of Medicine, University of Zagreb, Salata 11, Zagreb 10000, Croatia. sikiric@mef.hr
Keywords BPC 157; Vessels; Perforated cecum; L-arginine; L-NAME; Rats
Core Tip In rats, the cecum was exposed, and a perfo­ration (5-mm diameter) was made at the ventral face of the basal region of the cecum close to the largest curvature. After 1 min, a bath (1 ml/rat) containing BPC 157, L-NAME, L-arginine, saline (controls) was directly applied to the perforated cecum, alone or in combination. Previously, BPC 157 rapidly activated the collateral circulation from existing vessels in ischemic colitis or inferior caval vein occlusion (by passing through the arcade vessels or the left ovarian vein and other veins) to reestablish blood flow and exert its free radical scavenger effect in both ischemia and reperfusion.
Publish Date 2018-12-27 08:56
Citation Drmic D, Samara M, Vidovic T, Malekinusic D, Antunovic M, Vrdoljak B, Ruzman J, Milkovic Perisa M, Horvat Pavlov K, Jeyakumar J, Seiwerth S, Sikiric P. Counteraction of perforated cecum lesions in rats: effects of pentadecapeptide BPC 157, L-NAME and L-arginine. World J Gastroenterol 2018; 24(48): 5462-5476
Url https://www.wjgnet.com/1007-9327/full/v24/i48/5462.htm
DOI https://dx.doi.org/10.3748/wjg.v24.i48.5462
Full Article (PDF) WJG-24-5462.pdf
Full Article (Word) WJG-24-5462.docx
Manuscript File 41644-Review.docx
Answering Reviewers 41644-Answering reviewers.pdf
Audio Core Tip 41644-Audio core tip.mp3
Biostatistics Review Certificate 41644-Biostatistics Review Certificate.docx
Conflict-of-Interest Disclosure Form 41644-Conflict-of-interest statement.pdf
Copyright License Agreement 41644-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 41644-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 41644-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 41644-Language certificate.pdf
Peer-review Report 41644-Peer-review(s).pdf
Scientific Misconduct Check 41644-Scientific misconduct check.pdf
Scientific Editor Work List 41644-Scientific editor work list.pdf