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Articles Published Processes
1/26/2019 5:26:31 AM | Browse: 865 | Download: 1060
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Received |
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2018-09-03 01:26 |
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Peer-Review Started |
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2018-09-03 05:46 |
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To Make the First Decision |
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2018-10-22 00:36 |
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Return for Revision |
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2018-10-26 10:34 |
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Revised |
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2018-11-11 02:59 |
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Second Decision |
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2018-12-14 06:55 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-12-17 05:16 |
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Articles in Press |
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2018-12-17 05:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-12-28 01:27 |
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Typeset the Manuscript |
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2019-01-24 07:11 |
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Publish the Manuscript Online |
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2019-01-26 05:26 |
| ISSN |
2218-6255 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Respiratory System |
| Manuscript Type |
Review |
| Article Title |
Anatomical backgrounds on gas exchange parameters in the lung
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Kazuhiro Yamaguchi, Takao Tsuji, Kazutetsu Aoshiba, Hiroyuki Nakamura and Shinji Abe |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Kazuhiro Yamaguchi, FCCP, MD, PhD, Professor, Department of Respiratory Medicine, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Tokyo 160-0023, Japan. yamaguc@sirius.ocn.ne.jp |
| Key Words |
Secondary lobule of Miller; Acinus of Loeschke; Acinus of Aschoff; Convection; Gas-phase diffusion (stratification); Aqueous-phase diffusion; Ventilation-perfusion heterogeneity |
| Core Tip |
The anatomical gas-exchange unit is organized into the acinus of Loeschcke, while the functional gas-exchange unit is given by the acinus of Aschoff. The ventilation-perfusion distribution in acinar regions is representatively predicted from the inert-gas elimination technique. The effective alveolar-arterial PO2 difference plays a vital role in detecting moderately low ventilation-perfusion regions eliciting hypoxemia but not very low and high ventilation-perfusion regions. Pulmonary diffusing capacity for CO and the value corrected for alveolar volume estimate the impediment of alveolar walls and are more sensitive to detecting the abnormality of pulmonary microcirculation than that of alveolocapillary membrane. |
| Publish Date |
2019-01-26 05:26 |
| Citation |
Yamaguchi K, Tsuji T, Aoshiba K, Nakamura H, Abe S. Anatomical backgrounds on gas exchange parameters in the lung. World J Respirol 2019; 9(2): 8-29 |
| URL |
https://www.wjgnet.com/2218-6255/full/v9/i2/8.htm |
| DOI |
https://dx.doi.org/10.5320/wjr.v9.i2.8 |
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