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Articles Published Processes
1/15/2019 3:31:05 AM | Browse: 1136 | Download: 1817
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Received |
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2018-08-21 10:40 |
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Peer-Review Started |
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2018-08-22 08:56 |
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To Make the First Decision |
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2018-10-12 00:13 |
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Return for Revision |
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2018-10-14 06:33 |
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Revised |
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2018-11-15 07:46 |
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Second Decision |
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2019-01-08 10:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-01-08 21:42 |
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Articles in Press |
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2019-01-08 21:42 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-01-14 00:36 |
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Publish the Manuscript Online |
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2019-01-15 03:31 |
| ISSN |
2218-6263 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Dentistry, Oral Surgery & Medicine |
| Manuscript Type |
Review |
| Article Title |
Dental pulp stem cells: Novel cell-based and cell-free therapy for peripheral nerve repair
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Nessma Sultan, Laila E Amin, Ahmed R Zaher, Ben A Scheven and Mohammed E Grawish |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mohammed E Grawish, PhD, Professor, Department of Oral Biology, Faculty of Dentistry, Mansoura University, El-Gomhoria Street, Mansoura, Egypt, Mansoura 35516, Egypt. grawish2004@mans.edu.eg |
| Key Words |
Dental pulp stem cells; Secretomes; Cell-based therapy; Cell-free therapy; Peripheral nerve injury |
| Core Tip |
The distinct developmental pathway of dental pulp stem cells (DPSCs) from neural crest cells results in a cell type that can be participate in neural tissue regeneration. The efficacy of using DPSCs for peripheral nerve repair (PNR) is strongly influenced by boosting trophic factors that promote axonal growth and regeneration and provide direct and indirect protection against cell death. Recently, encouraging results from different studies indicate that DPSC secretomes have reparative and protective properties comparable with their cellular counterparts in PNR. The use of DPSC secretomes as a safe and possibly more valuable substitute for cell-based therapy approaches is a novel therapeutic perspective. |
| Publish Date |
2019-01-15 03:31 |
| Citation |
Sultan N, Amin LE, Zaher AR, Scheven BA, Grawish ME. Dental pulp stem cells: Novel cell-based and cell-free therapy for peripheral nerve repair. World J Stomatol 2019; 7(1): 1-19 |
| URL |
https://www.wjgnet.com/2218-6263/full/v7/i1/1.htm |
| DOI |
https://dx.doi.org/10.5321/wjs.v7.i1.1 |
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