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Articles Published Processes
12/13/2018 6:32:35 AM | Browse: 613 | Download: 2078
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Received |
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2018-09-04 01:43 |
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Peer-Review Started |
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2018-09-04 06:34 |
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To Make the First Decision |
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2018-10-08 02:11 |
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Return for Revision |
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2018-10-09 00:45 |
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Revised |
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2018-10-31 03:02 |
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Second Decision |
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2018-11-07 09:11 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-11-08 02:35 |
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Articles in Press |
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2018-11-08 02:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-11-27 01:54 |
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Typeset the Manuscript |
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2018-12-12 03:44 |
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Publish the Manuscript Online |
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2018-12-13 06:32 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
MicroRNA-15a - cell division cycle 42 signaling pathway in pathogenesis of pediatric inflammatory bowel disease
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wen-Juan Tang, Kai-Yue Peng, Zi-Fei Tang, Yu-Huan Wang, Ai-Juan Xue and Ying Huang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Natural Science Foundation of Shanghai |
201540068 |
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| Corresponding Author |
Ying Huang, MD, PhD, Chief Doctor, Director, Professor, Department of Gastroenterology, Children’s Hospital of Fudan University, 399 Wanyuan Road, Shanghai 201102, China. 15111240011@fudan.edu.cn |
| Key Words |
Pediatric inflammatory bowel disease; MicroRNA-15a; Cell division cycle 42; Zona occludens-1; E-cadherin |
| Core Tip |
This study aimed to determine whether cell division cycle (Cdc)42 was regulated by microRNAs in pediatric inflammatory bowel disease (IBD) development. We studied microRNA (miR)-15a - Cdc42 signaling in pediatric IBD patients and found that miR-15a negatively regulated Cdc42 in pediatric IBD patients, and both were strongly correlated with the severity of IBD. Additionally, this study provides evidence that Cdc42 is a target gene of miR-15a, and this will provide a critical clue for understanding IBD development. |
| Publish Date |
2018-12-13 06:32 |
| Citation |
Tang WJ, Peng KY, Tang ZF, Wang YH, Xue AJ, Huang Y. MicroRNA-15a - cell division cycle 42 signaling pathway in pathogenesis of pediatric inflammatory bowel disease. World J Gastroenterol 2018; 24(46): 5234-5245 |
| URL |
https://www.wjgnet.com/1007-9327/full/v24/i46/5234.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v24.i46.5234 |
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