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11/21/2018 4:08:59 AM | Browse: 131 | Download: 67
Publication Name World Journal of Gastroenterology
Manuscript ID 41811
Country of Manuscript Source Czech Republic
2018-08-31 11:28
Peer-Review Started
2018-09-02 06:20
To Make the First Decision
2018-10-08 02:37
Return for Revision
2018-10-14 06:41
2018-10-20 20:56
Second Decision
2018-11-13 08:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-11-13 21:53
Articles in Press
2018-11-13 21:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-11-16 05:57
Publish the Manuscript Online
2018-11-21 04:08
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Transplantation
Manuscript type Retrospective Study
Article Title Risk of recurrence of primary sclerosing cholangitis after liver transplantation is associated with de novo inflammatory bowel disease
Manuscript Source Invited Manuscript
All Author List Lukas Bajer, Antonij Slavcev, Peter Macinga, Eva Sticova, Jan Brezina, Matej Roder, Radim Janousek, Pavel Trunecka, Julius Spicak and Pavel Drastich
Author(s) ORCID Number
Lukas Bajer http://orcid.org/0000-0002-3815-3120
Antonij Slavcev http://orcid.org/0000-0002-6154-9131
Peter Macinga http://orcid.org/0000-0003-3699-6914
Eva Sticova http://orcid.org/0000-0003-2486-6266
Jan Brezina http://orcid.org/0000-0002-0440-9220
Matej Roder http://orcid.org/0000-0002-3677-3473
Radim Janousek http://orcid.org/0000-0003-2735-9403
Pavel Trunecka http://orcid.org/0000-0002-4753-4419
Julius Spicak http://orcid.org/0000-0002-3823-2881
Pavel Drastich http://orcid.org/0000-0002-5656-9242
Funding Agency and Grant Number
Funding Agency Grant Number
Ministry of Health of the Czech Republic 15-28064A
Ministry of Health of the Czech Republic 16-27477A
Correspondence To Lukas Bajer, MD, Doctor, Department of Gastroenterology and Hepatology, Institute for Clinical and Experimental Medicine, Videnska 9, Prague 14021, Czech Republic. lukasbajer1@gmail.com
Keywords Primary sclerosing cholangitis; Inflammatory bowel disease; Liver transplantation; Acute cellular rejection; Autoimmune hepatitis; Human leukocyte antigen; Immunosuppression
Core Tip This study demonstrates that patients with de novo colitis after liver transplantation for primary sclerosing cholangitis (PSC) are significantly predisposed towards primary liver disease recurrence (rPSC). History of acute cellular rejection of the liver graft, overlapping features of autoimmune hepatitis (autoimmune hepatitis /PSC) and certain human leukocyte antigen (HLA)-DQ and HLA-DR alleles in both donors and recipients may also have an impact on rPSC development. These data based on analysis of well-defined cohort with long median follow-up suggest that thorough routine endoscopic, radiological and immunological examination (both pre- and post-transplant) is crucial for identifying high-risk patients.
Publish Date 2018-11-21 04:08
Citation Bajer L, Slavcev A, Macinga P, Sticova E, Brezina J, Roder M, Janousek R, Trunecka P, Spicak J, Drastich P. Risk of recurrence of primary sclerosing cholangitis after liver transplantation is associated with de novo inflammatory bowel disease. World J Gastroenterol 2018; 24(43): 4939-4949
Url http://www.wjgnet.com/1007-9327/full/v24/i43/4939.htm
DOI http://dx.doi.org/10.3748/wjg.v24.i43.4939
Full Article (PDF) WJG-24-4939.pdf
Full Article (Word) WJG-24-4939.doc
Manuscript File 41811-Review.docx
Answering Reviewers 41811-Answering reviewers.pdf
Audio Core Tip 41811-Audio core tip.mp3
Biostatistics Review Certificate 41811-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 41811-Conflict-of-interest statement.pdf
Copyright License Agreement 41811-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 41811-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 41811-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 41811-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 41811-Language certificate.pdf
Peer-review Report 41811-Peer-review(s).pdf
Scientific Misconduct Check 41811-Scientific misconduct check.pdf
Scientific Editor Work List 41811-Scientific editor work list.pdf