Publication Name	World Journal of Gastroenterology
Manuscript ID	41851
Country	United States

Received	2018-08-28 01:46
Peer-Review Started	2018-08-28 07:13
To Make the First Decision	2018-10-08 02:58
Return for Revision	2018-10-09 02:01
Revised	2018-10-12 21:42
Second Decision	2018-10-19 09:30
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-10-21 06:32
Articles in Press	2018-10-21 06:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-11-09 05:54
Publish the Manuscript Online	2018-11-13 08:04

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Increased susceptibility of aging gastric mucosa to injury and delayed healing: Clinical implications
Manuscript Source	Invited Manuscript
All Author List	Andrzej S Tarnawski and Amrita Ahluwalia
ORCID	Author(s) ORCID Number Andrzej S Tarnawski http://orcid.org/0000-0002-6813-6698 Amrita Ahluwalia http://orcid.org/0000-0002-2064-5725
Funding Agency and Grant Number	Funding Agency Grant Number US Department of Veterans Affairs BX000626-05A2
Corresponding Author	Andrzej S Tarnawski, DSc, FACG, MD, PhD, Professor, Department of Gastroenterology Research, University of California Irvine and the Veterans Administration Long Beach Healthcare System, 5901 E. Seventh Street, Long Beach, CA 90822, United States. atarnawski@yahoo.com
Key Words	Aging gastric mucosa; Injury; Low dose aspirin; Platelets; Cyclooxygenase-1; Cyclooxygenase-2; Thromboxane A-2
Core Tip	Low dose aspirin is widely used to prevent cardiovascular events such as myocardial infarcts and strokes; however, this therapy significantly increases the risk of gastrointestinal injury and induces ulceration and serious bleeding especially in aging individuals. This risk is further increased in patients using low dose aspirin concurrently with other antiplatelet agents, other nonsteroidal anti-inflammatory agents and/or alcohol, or in patients with Helicobacter pylori infection.
Publish Date	2018-11-13 08:04
Citation	Tarnawski AS, Ahluwalia A. Increased susceptibility of aging gastric mucosa to injury and delayed healing: Clinical implications. World J Gastroenterol 2018; 24(42): 4721-4727
URL	http://www.wjgnet.com/1007-9327/full/v24/i42/4721.htm
DOI	http://dx.doi.org/10.3748/wjg.v24.i42.4721

Full Article (PDF)	WJG-24-4721.pdf
Full Article (Word)	WJG-24-4721.doc
Manuscript File	41851-Review.docx
Answering Reviewers	41851-Answering reviewers.pdf
Audio Core Tip	41851-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	41851-Conflict-of-interest statement.pdf
Copyright License Agreement	41851-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	41851-Grant application form(s).pdf
Peer-review Report	41851-Peer-review(s).pdf
Scientific Misconduct Check	41851-Scientific misconduct check.pdf
Scientific Editor Work List	41851-Scientific editor work list.pdf