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Articles Published Processes
2/26/2019 11:29:05 AM | Browse: 1093 | Download: 1553
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Received |
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2018-08-29 01:35 |
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Peer-Review Started |
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2018-08-29 06:25 |
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To Make the First Decision |
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2018-10-19 06:05 |
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Return for Revision |
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2018-10-19 09:52 |
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Revised |
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2018-11-19 18:34 |
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Second Decision |
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2019-01-22 10:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-01-28 21:58 |
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Articles in Press |
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2019-01-28 21:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-02-24 06:13 |
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Publish the Manuscript Online |
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2019-02-26 11:29 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Hepatic encephalopathy: Lessons from preclinical studies
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Luiza Cioglia Dias Lima, Aline Silva Miranda, Rodrigo Novaes Ferreira, Milene Alvarenga Rachid and Ana Cristina Simoes e Silva |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ana Cristina Simoes e Silva, MD, PhD, Full Professor, Laboratório Interdisciplinar de Investigação Médica, Faculdade de Medicina, UFMG, Avenida Alfredo Balena, 190, 2o andar, sala 281, Belo Horizonte 30130-100, Minas Geris, Brazil. acssilva@hotmail.com |
| Key Words |
Hepatic encephalopathy; Acute liver failure; Preclinical studies; Hepatic cirrhosis; Neuroinflammation; Hyperammonemia |
| Core Tip |
Hepatic encephalopathy (HE) is a major complication closely related to the progression of end-stage liver disease. It can be subdivided according to the type of hepatic injury: type A, which results from acute liver failure, type B, which is associated with a portosystemic shunting without intrinsic liver disease, and type C, which is due to chronic liver disease. In this article, we have described the use of preclinical models to investigate HE. We have briefly described the applicability and the characteristics of these experimental models. In conclusion, preclinical models have allowed the comprehension of the pathways related to HE. |
| Publish Date |
2019-02-26 11:29 |
| Citation |
Lima LCD, Miranda AS, Ferreira RN, Rachid MA, Simões e Silva AC. Hepatic encephalopathy: Lessons from preclinical studies. World J Hepatol 2019; 11(2): 173-185 |
| URL |
https://www.wjgnet.com/1948-5182/full/v11/i2/173.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v11.i2.173 |
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