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Articles Published Processes
9/12/2014 8:41:00 PM | Browse: 1370 | Download: 1269
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Received |
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2013-06-19 19:02 |
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Peer-Review Started |
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2013-06-20 12:55 |
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To Make the First Decision |
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2013-09-09 16:53 |
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Return for Revision |
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2013-09-15 18:55 |
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Revised |
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2013-10-02 15:09 |
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Second Decision |
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2013-10-21 17:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-10-22 07:14 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-11-04 13:55 |
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Publish the Manuscript Online |
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2013-11-18 10:59 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Pharmacological challenges in chronic pancreatitis
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Manuscript Source |
Invited Manuscript |
All Author List |
Anne Estrup Olesen, Anne Brokjaer, Iben Wendelboe Fisher and Isabelle Myriam Larsen |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Danish Council for Strategic Research |
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Corresponding Author |
Anne Estrup Olesen, MSc (pharm), PhD, Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Mølleparkvej 4, 9000 Aalborg, Denmark. aneso@rn.dk |
Key Words |
Pharmacology; Absorption; Metabolism; Chronic pancreatitis; Treatment |
Core Tip |
In patients with chronic pancreatitis several pathophysiological factors can account for malabsorption and may also affect the efficacy of pharmacological intervention by reduced drug absorption. For example it can be speculated that changes in gastrointestinal intraluminal pH, motility disorder, bacterial overgrowth and changed pancreatic gland secretion may contribute. The lifestyle of chronic pancreatitis patients may also be a factor to gastrointestinal changes. The factors may not have clinical relevance, but may explain inter-individual variations in responses to a given drug, in patients with chronic pancreatitis. |
Publish Date |
2013-11-18 10:59 |
Citation |
Olesen AE, Brokjaer A, Fischer IW, Larsen IM. Pharmacological challenges in chronic pancreatitis. World J Gastroenterol 2013; 19(42): 7302-7307 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i42/7302.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i42.7302 |
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