Category |
Gastroenterology & Hepatology |
Manuscript Type |
Autobiography |
Article Title |
Nonalcoholic fatty liver disease is associated with coronary artery disease in Koreans
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Manuscript Source |
Invited Manuscript |
All Author List |
Dae Hee Choi, Sung Joon Lee, Chang Don Kang, Myoung Ok Park, Dong Wook Choi, Tae Suk Kim, Wonho Lee, Byung Ryul Cho, Yong Hoon Kim, Bong-ki Lee, Dong Ryeol Ryu and Ji Won Lee |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
A 2009 Research Grant from Kangwon National University |
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Corresponding Author |
Dong Ryeol Ryu, MD, Associate Professor of Internal Medicine, Department of Internal Medicine, Kangwon National University School of Medicine, Hyoja-dong, Chuncheon 200-701, South Korea. rdr0203@hanmail.net |
Key Words |
Nonalcoholic fatty liver disease; Coronary artery disease; Coronary angiography; Adiponectin; Insulin resistance |
Core Tip |
This article shows that angiographically proven coronary artery stenosis is strongly associated with nonalcoholic fatty liver disease (NAFLD) in a grade-dependent manner. Although many recent studies used coronary artery calcification score, carotid artery intima-media thickness, or carotid artery plaque measurements as surrogate markers for coronary artery disease (CAD), we evaluated the interaction between fatty liver and cardiovascular outcomes using coronary angiograms in a prospective case-controlled study. Because the pathogenesis of NAFLD and CAD is not fully elucidated, we attempted to identify mediators of these diseases and believe that adiponectin might be related to the development and progression of CAD in patients with NAFLD.
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Publish Date |
2013-10-15 17:26 |
Citation |
Choi DH, Lee SJ, Kang CD, Park MO, Choi DW, Kim TS, Lee W, Cho BR, Kim YH, Lee B, Ryu DR, Lee JW. Nonalcoholic fatty liver disease is associated with coronary artery disease in Koreans. World J Gastroenterol 2013; 19(38): 6453-6457 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i38/6453.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i38.6453 |