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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 42297
Country/Territory France
Received
2018-10-02 10:03
Peer-Review Started
2018-10-02 11:22
To Make the First Decision
2018-10-29 03:06
Return for Revision
2018-10-31 07:36
Revised
2018-11-27 15:57
Second Decision
2018-12-29 02:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-01-01 03:07
Articles in Press
2019-01-01 03:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-01-11 22:23
Typeset the Manuscript
2019-04-15 02:29
Publish the Manuscript Online
2019-04-15 10:50
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Retrospective Cohort Study
Article Title Predictive factors of histological response of colorectal liver metastases after neoadjuvant chemotherapy
Manuscript Source Unsolicited Manuscript
All Author List Chloé Serayssol, Charlotte Maulat, Florence Breibach, Fatima-Zohra Mokrane, Janick Selves, Rosine Guimbaud, Philippe Otal, Bertrand Suc, Emilie Berard and Fabrice Muscari
ORCID
Author(s) ORCID Number
Chloé Serayssol http://orcid.org/0000-0001-9965-0908
Charlotte Maulat http://orcid.org/0000-0002-0384-6592
Florence Breibach http://orcid.org/0000-0003-2800-5615
Fatima-Zohra Mokrane http://orcid.org/0000-0003-1610-1474
Janick Selves http://orcid.org/0000-0001-6122-7004
Rosine Guimbaud http://orcid.org/0000-0002-8344-1762
Philippe Otal http://orcid.org/0000-0002-3590-8014
Bertrand Suc http://orcid.org/0000-0002-2292-1156
Emilie Berard http://orcid.org/0000-0003-2451-5271
Fabrice Muscari http://orcid.org/0000-0001-6754-1686
Funding Agency and Grant Number
Corresponding Author Charlotte Maulat, Academic Fellow, Department of Digestive Surgery and Liver Transplantation, Toulouse-Rangueil University Hospital, CHU Rangueil, 1 avenue Jean Poulhès, Toulouse 31059, France. charlotte.maulat@gmail.com
Key Words Colorectal liver metastasis; Tumor regression grade; Neoadjuvant chemotherapy; Liver surgery; Histological response; Hepatectomy
Core Tip In this study we analyzed the histological response of colorectal liver metastasis of 74 responders and 76 non-responders after neoadjuvant chemotherapy and identified that the absence of a radiological response and extended neoadjuvant chemotherapy, comprising more than seven treatment sessions, are the two most pertinent predictive factors of non-histological response. This study has also confirmed that the histological response of colorectal liver metastases after neoadjuvant chemotherapy has an influence on survival and hence warrants being considered. However, this influence on overall survival was lacking in cases of particularly aggressive disease with microscopic vascular invasion on the histological analysis.
Publish Date 2019-04-15 10:50
Citation Serayssol C, Maulat C, Breibach F, Mokrane FZ, Selves J, Guimbaud R, Otal P, Suc B, Berard E, Muscari F. Predictive factors of histological response of colorectal liver metastases after neoadjuvant chemotherapy. World J Gastrointest Oncol 2019; 11(4): 295-309
URL https://www.wjgnet.com/1948-5204/full/v11/i4/295.htm
DOI https://dx.doi.org/10.4251/wjgo.v11.i4.295
Full Article (PDF) WJGO-11-295.pdf
Full Article (Word) WJGO-11-295.docx
STROBE Statement 42297-STROBE Statement.pdf
Manuscript File 42297-Review.doc
Answering Reviewers 42297-Answering reviewers.pdf
Audio Core Tip 42297-Audio core tip.mp3
Biostatistics Review Certificate 42297-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 42297-Conflict-of-interest statement.pdf
Copyright License Agreement 42297-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 42297-Approved-Grant-Application-Form(s)-or-Funding-Agency-Copy-of-any-Approval-Document(s)-revision.pdf
Signed Informed Consent Form(s) or Document(s) 42297-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 42297-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 42297-Language certificate.pdf
Peer-review Report 42297-Peer-review(s).pdf
Scientific Misconduct Check 42297-Scientific misconduct check.pdf
Scientific Editor Work List 42297-Scientific editor work list.pdf