Publication Name	World Journal of Gastroenterology
Manuscript ID	4242
Country	Taiwan

Received	2013-06-22 16:09
Peer-Review Started	2013-06-22 21:15
To Make the First Decision	2013-08-08 11:29
Return for Revision	2013-08-16 19:46
Revised	2013-09-03 00:09
Second Decision	2013-09-17 09:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-09-17 11:22
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-03 12:52
Publish the Manuscript Online	2013-11-18 10:59

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Differentiation between dysplastic nodule and early-stage hepatocellular carcinoma: The utility of conventional MR imaging
Manuscript Source	Invited Manuscript
All Author List	Chen-Te Chou, Jung-Mao Chou, Ting-An Chang, Shiu-Feng Huang, Chia-Bang Chen, Yao-Li Chen and Ran-Chou Chen
Funding Agency and Grant Number
Corresponding Author	Ran-Chou Chen, MD, Department of Biomedical Imaging and Radiological Science, National Yang-Ming Medical University, Beitou District, Taipei 112, Taiwan. chenranchou@yahoo.com.tw
Key Words	Dysplastic nodule; Hepatocellular carcinoma; Histological grading; Magnetic resonance imaging; Well-differentiated hepatocellular carcinoma
Core Tip	The aim of this article was to differentiate between early-stage hepatocellular carcinoma (HCC) and dysplastic nodules using conventional magnetic resonance (MR) imaging. We found that conventional MR imaging could provide additional information to differentiate between early-stage HCC and dysplastic nodules in equivocal lesions. During follow-up for a cirrhotic nodules, increased signal intensity on T2-weighted axial images may be a sign of malignant transformation. Loss of hyperintensity on T1WI and the detection of arterial enhancement may indicate further progression of the histological grade.
Publish Date	2013-11-18 10:59
Citation	Chou CT, Chou JM, Chang TA, Huang SF, Chen CB, Chen YL, Chen RC. Differentiation between dysplastic nodule and early-stage hepatocellular carcinoma: The utility of conventional MR imaging. World J Gastroenterol 2013; 19(42): 7433-7439
URL	http://www.wjgnet.com/1007-9327/full/v19/i42/7433.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i42.7433

Full Article (PDF)	WJG-19-7433.pdf
Manuscript File	4242-Review.doc
Answering Reviewers	4242-Answering reviewers.pdf
Copyright License Agreement	4242-Copyright assignment.doc
Non-Native Speakers of English Editing Certificate	4242-Language certificate.doc
Peer-review Report	4242-Peer review(s).pdf
Scientific Editor Work List	4242-Scientific editor work list.doc