Publication Name	World Journal of Experimental Medicine
Manuscript ID	4250
Country	Greece

Received	2013-06-24 08:57
Peer-Review Started	2013-06-24 23:03
To Make the First Decision	2013-07-05 18:23
Return for Revision	2013-07-15 22:37
Revised	2013-07-19 19:56
Second Decision	2013-08-16 19:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-08-17 00:45
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-08-26 13:49
Publish the Manuscript Online	2013-09-14 11:34

ISSN	2220-315x (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Endocrinology & Metabolism
Manuscript Type	Editorial
Article Title	Interplay of adipokines and myokines in cancer pathophysiology: Emerging therapeutic implications
Manuscript Source	Invited Manuscript
All Author List	Maria Dalamaga
Funding Agency and Grant Number
Corresponding Author	Maria Dalamaga, MD, PhD, MS, MPH, Assistant Professor, Department of Clinical Biochemistry, Medical School, University of Athens, “Attikon” General University Hospital, 1 Rimini Street, 12462 Athens, Greece. madalamaga@med.uoa.gr
Key Words	Adipokine; Myokine; Cancer; Cachexia; Interleukin-15; Interleukin-6; Obesity; Myostatin
Core Tip	The complex paracrine and endocrine interconnection between adipokines and myokines reflects a yin-yang balance with important implications in processes such as lipolysis control, insulin sensitivity and prevention from obesity-driven chronic low-grade inflammation and cancer promotion through anti-inflammatory adipokines and myokines. In addition, the complex pathophysiology of cancer cachexia is based on the interplay between muscle and adipose tissue mediated by free fatty acids, various adipokines and myokines. Advances in the field of translational investigation may lead to tangible benefits to obese and inactive persons who are at increased risk of cancer as well as to cancer patients with cachexia.
Publish Date	2013-09-14 11:34
Citation	Dalamaga M. Interplay of adipokines and myokines in cancer pathophysiology: Emerging therapeutic implications. World J Exp Med 2013; 3(3): 26-33
URL	http://www.wjgnet.com/2220-315X/full/v3/i3/26.htm
DOI	http://dx.doi.org/10.5493/wjem.v3.i3.26

Full Article (PDF)	WJEM-3-26.pdf
Manuscript File	4250-Review.docx
Answering Reviewers	4250-Answering reviewers.pdf
Biostatistics Review Certificate	editorial and biostatistics.docx
Copyright License Agreement	4250-Copyright assignment.doc
Institutional Review Board Approval Form or Document	editorial and ethics committee.docx
Non-Native Speakers of English Editing Certificate	editorial and language editing.docx
Peer-review Report	4250-Peer review(s).pdf
Scientific Editor Work List	4250-Scientific editor work list.doc