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Articles Published Processes
1/27/2019 7:04:05 AM | Browse: 974 | Download: 1391
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Received |
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2018-09-27 03:36 |
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Peer-Review Started |
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2018-09-27 04:25 |
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To Make the First Decision |
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2018-10-17 01:28 |
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Return for Revision |
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2018-10-19 04:32 |
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Revised |
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2018-11-14 01:09 |
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Second Decision |
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2018-12-29 02:13 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-01-01 05:56 |
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Articles in Press |
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2019-01-01 05:56 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-01-24 09:03 |
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Publish the Manuscript Online |
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2019-01-27 07:04 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Minireviews |
Article Title |
Persistent risk for new, subsequent new and recurrent hepatocellular carcinoma despite successful anti-hepatitis B virus therapy and tumor ablation: The need for hepatitis B virus cure
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Brianna J Shinn, Aaron Martin, Robert M Coben, Mitchell I Conn, Jorge Prieto, Howard Kroop, Anthony J DiMarino and Hie-Won Hann |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Hie-Won Hann, Liver Disease Prevention Center, Division of Gastroenterology and Hepatology, Thomas Jefferson University Hospital, 1025 Walnut Street, Philadelphia, PA 19107, United States. hie-won.hann@jefferson.edu |
Key Words |
Hepatitis B; Hepatocellular carcinoma; Antiviral therapy; Persistent Risk for hepatocellular carcinoma; Tumor ablation |
Core Tip |
Despite the advances in the management of hepatitis B virus (HBV) infection and HBV-associated hepatocellular carcinoma (HCC), the risk for new, subsequent new and recurrent HCC persists even after over a decade of antiviral therapy and initial tumor ablation. This is due to the inability of the current antiviral therapy to eliminate the cccDNA from the hepatocyte nucleus. There is a great need for an HBV cure drug. |
Publish Date |
2019-01-27 07:04 |
Citation |
Shinn BJ, Martin A, Coben RM, Conn MI, Prieto J, Kroop H, DiMarino AJ, Hann HW. Persistent risk for new, subsequent new and recurrent hepatocellular carcinoma despite successful anti-hepatitis B virus therapy and tumor ablation: The need for hepatitis B virus cure. World J Hepatol 2019; 11(1): 65-73 |
URL |
https://www.wjgnet.com/1948-5182/full/v11/i1/65.htm |
DOI |
https://dx.doi.org/10.4254/wjh.v11.i1.65 |
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