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Articles Published Processes
1/27/2019 7:04:05 AM | Browse: 1040 | Download: 1612
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Received |
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2018-09-28 02:24 |
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Peer-Review Started |
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2018-09-28 08:07 |
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To Make the First Decision |
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2018-10-22 00:20 |
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Return for Revision |
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2018-10-24 03:04 |
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Revised |
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2018-11-13 16:19 |
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Second Decision |
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2018-12-03 00:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-12-05 17:44 |
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Articles in Press |
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2018-12-05 17:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-01-24 12:45 |
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Publish the Manuscript Online |
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2019-01-27 07:04 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Serum biomarkers and risk of hepatocellular carcinoma recurrence after liver transplantation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Maria Jesus Citores, Jose Luis Lucena, Sara de la Fuente and Valentin Cuervas-Mons |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Maria Jesus Citores, BSc, PhD, Research Scientist, Laboratory of Internal Medicine, Hospital Universitario Puerta de Hierro Majadahonda, Joaquin Rodrigo 2, Majadahonda 28222, Madrid, Spain. mariajesus.citores@salud.madrid.org |
| Key Words |
Hepatocellular carcinoma; Liver transplantation; Recurrence; Selection criteria; Prognostic score; Biomarker; Alpha-fetoprotein; Systemic inflammatory marker |
| Core Tip |
The Milan criteria for liver transplantation have improved survival of patients with small hepatocellular carcinoma (HCC), but up to 20% of patients still experience HCC recurrence after transplantation. Microvascular invasion and tumors with poor histologic grade of differentiation are the most important risk factors for HCC recurrence, but they are evidenced after surgery on explant pathology examination. Several surrogate pretransplant biomarkers, directly related with tumor biology or systemic inflammation markers conditioning tumor progression, have been suggested to identify, alone or integrated in pretransplant prognostic scores, patients at high risk of HCC recurrence after liver transplantation. |
| Publish Date |
2019-01-27 07:04 |
| Citation |
Citores MJ, Lucena JL, de la Fuente S, Cuervas-Mons V. Serum biomarkers and risk of hepatocellular carcinoma recurrence after liver transplantation. World J Hepatol 2019; 11(1): 50-64 |
| URL |
https://www.wjgnet.com/1948-5182/full/v11/i1/50.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v11.i1.50 |
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