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Articles Published Processes
1/14/2019 2:54:12 PM | Browse: 1308 | Download: 1733
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Received |
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2018-10-05 02:42 |
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Peer-Review Started |
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2018-10-05 10:51 |
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To Make the First Decision |
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2018-11-15 03:37 |
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Return for Revision |
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2018-11-15 05:58 |
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Revised |
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2018-12-24 07:44 |
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Second Decision |
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2018-12-27 11:08 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2018-12-28 05:08 |
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Articles in Press |
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2018-12-28 05:08 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-01-14 00:01 |
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Publish the Manuscript Online |
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2019-01-14 14:54 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Current status, problems, and perspectives of non-alcoholic fatty liver disease research
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Naoki Tanaka, Takefumi Kimura, Naoyuki Fujimori, Tadanobu Nagaya, Michiharu Komatsu and Eiji Tanaka |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Naoki Tanaka, MD, PhD, Associate Professor, Doctor, Doctor, Department of Metabolic Regulation, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan. naopi@shinshu-u.ac.jp |
| Key Words |
Non-alcoholic steatohepatitis; Fibrosis; Steatosis; Ballooning; Biomarker; Outcome; Treatment |
| Core Tip |
Recent trends in diet and lifestyle have increased the prevalence of non-alcoholic fatty liver disease/steatohepatitis (NAFLD/NASH) worldwide. Although advances in non-invasive biomarkers and imaging modalities have improved disease detection and follow-up, considerable work is needed to identify individuals with low fibrosis stages or at risk of rapid disease progression. In the future, earlier detection will enable prompt single or combination treatment with new-line drugs that have been optimized for maximum benefit and fewer adverse events. Only with a concerted effort across multi-disciplinary fields can clinicians begin to halt the rapid spread of NAFLD/NASH. |
| Publish Date |
2019-01-14 14:54 |
| Citation |
Tanaka N, Kimura T, Fujimori N, Nagaya T, Komatsu M, Tanaka E. Current status, problems, and perspectives of non-alcoholic fatty liver disease research. World J Gastroenterol 2019; 25(2): 163-177 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i2/163.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i2.163 |
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