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1/14/2019 2:54:12 PM | Browse: 1133 | Download: 1354
Publication Name World Journal of Gastroenterology
Manuscript ID 42631
Country Japan
Received
2018-10-05 02:42
Peer-Review Started
2018-10-05 10:51
To Make the First Decision
2018-11-15 03:37
Return for Revision
2018-11-15 05:58
Revised
2018-12-24 07:44
Second Decision
2018-12-27 11:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-28 05:08
Articles in Press
2018-12-28 05:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-01-14 00:01
Publish the Manuscript Online
2019-01-14 14:54
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Current status, problems, and perspectives of non-alcoholic fatty liver disease research
Manuscript Source Invited Manuscript
All Author List Naoki Tanaka, Takefumi Kimura, Naoyuki Fujimori, Tadanobu Nagaya, Michiharu Komatsu and Eiji Tanaka
ORCID
Author(s) ORCID Number
Naoki Tanaka http://orcid.org/0000-0002-0606-2101
Takefumi Kimura http://orcid.org/0000-0002-1481-1029
Naoyuki Fujimori http://orcid.org/0000-0001-8744-8139
Tadanobu Nagaya http://orcid.org/0000-0002-0091-8343
Michiharu Komatsu http://orcid.org/0000-0002-7860-2816
Eiji Tanaka http://orcid.org/0000-0002-0724-2104
Funding Agency and Grant Number
Corresponding Author Naoki Tanaka, MD, PhD, Associate Professor, Doctor, Department of Metabolic Regulation, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan. naopi@shinshu-u.ac.jp
Key Words Non-alcoholic steatohepatitis; Fibrosis; Steatosis; Ballooning; Biomarker; Outcome; Treatment
Core Tip Recent trends in diet and lifestyle have increased the prevalence of non-alcoholic fatty liver disease/steatohepatitis (NAFLD/NASH) worldwide. Although advances in non-invasive biomarkers and imaging modalities have improved disease detection and follow-up, considerable work is needed to identify individuals with low fibrosis stages or at risk of rapid disease progression. In the future, earlier detection will enable prompt single or combination treatment with new-line drugs that have been optimized for maximum benefit and fewer adverse events. Only with a concerted effort across multi-disciplinary fields can clinicians begin to halt the rapid spread of NAFLD/NASH.
Publish Date 2019-01-14 14:54
Citation Tanaka N, Kimura T, Fujimori N, Nagaya T, Komatsu M, Tanaka E. Current status, problems, and perspectives of non-alcoholic fatty liver disease research. World J Gastroenterol 2019; 25(2): 163-177
URL https://www.wjgnet.com/1007-9327/full/v25/i2/163.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i2.163
Full Article (PDF) WJG-25-163.pdf
Full Article (Word) WJG-25-163.docx
Manuscript File 42631-Review.docx
Answering Reviewers 42631-Answering reviewers.pdf
Audio Core Tip 42631-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 42631-Conflict-of-interest statement.pdf
Copyright License Agreement 42631-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 42631-Language certificate.pdf
Supplementary Material 42631-Supplementary-Material-revision.docx
Peer-review Report 42631-Peer-review(s).pdf
Scientific Misconduct Check 42631-Scientific misconduct check.pdf
Scientific Editor Work List 42631-Scientific editor work list.pdf