Publication Name	World Journal of Gastroenterology
Manuscript ID	42696
Country	Pakistan

Received	2018-10-13 08:43
Peer-Review Started	2018-10-14 04:37
To Make the First Decision	2018-11-01 06:43
Return for Revision	2018-11-14 07:35
Revised	2018-12-19 06:42
Second Decision	2018-12-27 11:04
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-12-28 05:08
Articles in Press	2018-12-28 05:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-01-29 06:56
Publish the Manuscript Online	2019-01-30 05:59

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Functional gastrointestinal disorders and gut-brain axis: What does the future hold?
Manuscript Source	Invited Manuscript
All Author List	Kashif Mukhtar, Hasham Nawaz and Shahab Abid
ORCID	Author(s) ORCID Number Kashif Mukhtar http://orcid.org/0000-0002-0320-1030 Hasham Nawaz http://orcid.org/0000-0003-4289-8069 Shahab Abid http://orcid.org/0000-0003-2520-0378
Funding Agency and Grant Number
Corresponding Author	Shahab Abid, FACG, FCPS, MBBS, MD, PhD, Professor, Section of Gastroenterology at Department of Medicine, Aga Khan University, Stadium Road, Karachi 74800, Pakistan. shahab.abid@aku.edu
Key Words	Functional gastrointestinal disorders; Idiopathic bowel syndrome; Gut-brain axis; Microbiome-gut-brain axis; Machine learning; Artificial intelligence
Core Tip	The multifactorial nature of functional gastrointestinal disorders makes the diagnosis challenging. The identification of pathogenic microbiome signatures, combined with demographical, immunologic and neuroimaging findings can be encoded into machine learning algorithms which may help identify trends and patterns that can be studied to further our understanding of these disorders. These patterns can help determine the causality or can guide further research.
Publish Date	2019-01-30 05:59
Citation	Mukhtar K, Nawaz H, Abid S. Functional gastrointestinal disorders and gut-brain axis: what does the future hold? World J Gastroenterol 2019; 25(5): 552-566
URL	https://www.wjgnet.com/1007-9327/full/v25/i5/552.htm
DOI	https://dx.doi.org/10.3748/wjg.v25.i5.552

Full Article (PDF)	WJG-25-552.pdf
Full Article (Word)	WJG-25-552.docx
Manuscript File	42696-Review.docx
Answering Reviewers	42696-Answering reviewers.pdf
Audio Core Tip	42696-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	42696-Conflict-of-interest statement.pdf
Copyright License Agreement	42696-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	42696-Non-Native Speakers of English Editing Certificate.docx
Peer-review Report	42696-Peer-review(s).pdf
Scientific Misconduct Check	42696-Scientific misconduct check.pdf
Scientific Editor Work List	42696-Scientific editor work list.pdf