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9/15/2014 5:55:00 PM | Browse: 1385 | Download: 1358
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Received |
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2013-06-25 09:30 |
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Peer-Review Started |
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2013-06-25 14:28 |
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To Make the First Decision |
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2013-07-19 08:40 |
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Return for Revision |
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2013-09-16 11:00 |
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Revised |
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2013-08-01 17:52 |
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Second Decision |
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2013-09-16 13:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-09-17 05:23 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-10-15 16:47 |
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Publish the Manuscript Online |
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2013-10-31 14:50 |
Category |
Cell Biology |
Manuscript Type |
Review |
Article Title |
Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblasts
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Manuscript Source |
Invited Manuscript |
All Author List |
Maya Fakhry, Eva Hamade, Bassam Badran, René Buchet and David Magne |
Funding Agency and Grant Number |
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Corresponding Author |
David Magne, PhD, ICBMS, UMR CNRS 5246, University of Lyon 1, Bâtiment Raulin, 43 Bd du 11 novembre 1918, 69622 Villeurbanne Cedex, France. david.magne@univ-lyon1.fr |
Key Words |
Mesenchymal stem cells; Osteogenesis; Runt-related 2; Wnt; MicroRNAs |
Core Tip |
Several excellent reviews on the transcription factors involved in osteoblast differentiation have recently been published, but none also presented the microRNAs that control the expression of these transcription factors. Moreover, most of these reviews mainly reported mouse studies but important differences are well acknowledged between humans and mice. For instance vitamin D3, an important hormone controlling bone homeostasis, has very different effect in these species. Therefore, in the present review we particularly focus on human cells to present the transcription factors and MiRs controlling mesenchymal stem cells-osteoblastic differentiation. |
Publish Date |
2013-10-31 14:50 |
Citation |
Fakhry M, Hamade E, Badran B, Buchet R, Magne D. Molecular mechanisms of mesenchymal stem cell differentiation towards osteoblasts. World J Stem Cells 2013; 5(4): 136-148 |
URL |
http://www.wjgnet.com/1948-0210/full/v5/i4/136.htm |
DOI |
http://dx.doi.org/10.4252/wjsc.v5.i4.136 |
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