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Publication Name World Journal of Gastroenterology
Manuscript ID 4278
Country/Territory Japan
Received
2013-06-25 09:33
Peer-Review Started
2013-06-25 14:20
To Make the First Decision
2013-07-05 18:37
Return for Revision
2013-07-17 17:53
Revised
2013-08-02 19:25
Second Decision
2013-09-16 17:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-09-17 06:16
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-10-24 16:23
Publish the Manuscript Online
2013-12-18 09:53
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Branched-chain amino acids in liver diseases
Manuscript Source Invited Manuscript
All Author List Kazuto Tajiri and Yukihiro Shimizu
Funding Agency and Grant Number
Corresponding author Yukihiro Shimizu, MD, PhD, Gastroenterology Unit, Nanto Municipal Hospital, Nanto, Toyama 932-0211, Japan. rsf14240@nifty.com
Key Words Liver disease; Branched chain amino acids; Gene expression; Hepatocyte apoptosis; Hepatocyte regeneration; Immunity; Treatment
Core Tip Advanced liver diseases are commonly accompanied by nutritional disturbances, which worsen the prognosis of the patients. Serum levels of branched-chain amino acids (BCAAs) are decreased in patients with liver cirrhosis, and the amino acids imbalance could affect the clinical picture of the disease and the prognosis of the patients. However, there are few comprehensive reviews on the biological activities of BCAAs. In this review, we summarize the biological activities of BCAAs, and discuss possible applications of BCAAs for the management of patients with advanced liver diseases with a list of clinical trials of BCAA administration.
Publish Date 2013-12-18 09:53
Citation Tajiri K, Shimizu Y. Branched-chain amino acids in liver diseases. World J Gastroenterol 2013; 19(43): 7620-7629
Url http://www.wjgnet.com/1007-9327/full/v19/i43/7620.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i43.7620
Full Article (PDF) WJG-19-7620.pdf
Manuscript File 4278-Review.doc
Answering Reviewers 4278-Answering reviewers.pdf
Copyright License Agreement 4278-Copyright assignment.docx
Non-Native Speakers of English Editing Certificate 4278-Language certificate.pdf
Peer-review Report 4278-Peer reviewer(s).pdf
Scientific Editor Work List 4278-Scientific editor work list.doc